Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation

Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation

Item
http://www.wikidata.org/entity/Q24608910
Identification of H-Ras-specific motif for the activation of invasive signaling program in human breast epithelial cells.Antitumor activity of cell-permeable p18(INK4c) with enhanced membrane and tissue penetration.CDK4: A Key Player in the Cell Cycle, Development, and CancerThe prognostic significance and value of cyclin D1, CDK4 and p16 in human breast cancer.CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis.Cell cycle proteins as promising targets in cancer therapyDiscovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).Therapeutic strategies for targeting ras proteins.Kip3-ing kinetochores clustered.The steady-state level of CDK4 protein is regulated by antagonistic actions between PAQR4 and SKP2 and involved in tumorigenesis.Conditional expression of Ki-RasG12V in the mammary epithelium of transgenic mice induces estrogen receptor alpha (ERα)-positive adenocarcinoma.
P2860

Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation

Item
http://www.wikidata.org/entity/Q24608910
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2010 nî lūn-bûn
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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@ast
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@en
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
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type
label
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@ast
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@en
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@nl
prefLabel
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@ast
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@en
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Requirement of Cdk4 for v-Ha-r ...... e Program by the R24C Mutation
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932