Viral double-stranded RNAs from vaccinia virus early or intermediate gene transcripts possess PKR activating function, resulting in NF-kappaB activation, when the K1 protein is absent or mutated

Viral double-stranded RNAs from vaccinia virus early or intermediate gene transcripts possess PKR activating function, resulting in NF-kappaB activation, when the K1 protein is absent or mutated

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http://www.wikidata.org/entity/Q24609947
Locally Produced IL-10 Limits Cutaneous Vaccinia Virus SpreadPoxviral ankyrin proteinsPoxviruses and the evolution of host range and virulenceRecombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responsesOpposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus MutantsEctromelia virus accumulates less double-stranded RNA compared to vaccinia virus in BS-C-1 cells.Monkeypox virus induces the synthesis of less dsRNA than vaccinia virus, and is more resistant to the anti-poxvirus drug, IBT, than vaccinia virusThe C11R gene, which encodes the vaccinia virus growth factor, is partially responsible for MVA-induced NF-κB and ERK2 activation.Translation inhibition and stress granules in the antiviral immune response.Vaccinia virus encodes a novel inhibitor of apoptosis that associates with the apoptosome.Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis.Deletion of the K1L Gene Results in a Vaccinia Virus That Is Less Pathogenic Due to Muted Innate Immune Responses, yet Still Elicits Protective Immunity.KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation.Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory.Ectromelia virus lacking the E3L ortholog is replication-defective and nonpathogenic but does induce protective immunity in a mouse strain susceptible to lethal mousepox.
P2860

Viral double-stranded RNAs from vaccinia virus early or intermediate gene transcripts possess PKR activating function, resulting in NF-kappaB activation, when the K1 protein is absent or mutated

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http://www.wikidata.org/entity/Q24609947
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2011年論文
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2011年論文
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2011年論文
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Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@ast
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@en
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@nl
type
label
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@ast
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@en
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@nl
prefLabel
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@ast
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@en
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Viral double-stranded RNAs fro ...... 1 protein is absent or mutated
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932