Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice - Wikidata - wikimedia - TriplyDB

Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice

Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice

http://www.wikidata.org/entity/Q24615739

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RNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal Functions The Arc Gene Confers Genetic Susceptibility to Alzheimer's Disease in Han Chinese.Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation Alteration of the microRNA network during the progression of Alzheimer's disease.Competing targets of microRNA-608 affect anxiety and hypertension.The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity.Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing.A Systematic Investigation into Aging Related Genes in Brain and Their Relationship with Alzheimer's Disease The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing.Global identification of hnRNP A1 binding sites for SSO-based splicing modulation.Heterogeneous nuclear ribonucleoprotein A1 post-transcriptionally regulates Drp1 expression in neuroblastoma cells TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor.Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies.Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes.Post-transcriptional regulation by poly(ADP-ribosyl)ation of the RNA-binding proteins.U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis.Role of Sam68 in post-transcriptional gene regulation.Effects of rs3846662 Variants on HMGCR mRNA and Protein Levels and on Markers of Alzheimer's Disease Pathology.Neuronal AChE splice variants and their non-hydrolytic functions: redefining a target of AChE inhibitors?hnRNP A1: the Swiss army knife of gene expression.Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease.Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy.In silico analyses for molecular genetic mechanism and candidate genes in patients with Alzheimer's disease.Cholinergic modulation of the hippocampal region and memory function.Analysis of Differentially Expressed Genes Associated With Alzheimer's Disease Based on Bioinformatics Methods.Emerging bioinformatics approaches for analysis of NGS-derived coding and non-coding RNAs in neurodegenerative diseases.hnRNPA1 autoregulates its own mRNA expression to remain non-cytotoxic.CircRNAs in the brain.Faulty RNA splicing: consequences and therapeutic opportunities in brain and muscle disorders.Long Noncoding RNAs and RNA-Binding Proteins in Oxidative Stress, Cellular Senescence, and Age-Related Diseases.Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells.Alzheimer's brains show inter-related changes in RNA and lipid metabolism Stereotactic injection of microRNA-expressing lentiviruses to the mouse hippocampus ca1 region and assessment of the behavioral outcome Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders.Genetic mutations in RNA-binding proteins and their roles in ALS.Stress and Corticosteroids Modulate Muscarinic Long Term Potentiation (mLTP) in the Hippocampus.Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt-Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress.Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.

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Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice

http://www.wikidata.org/entity/Q24615739

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2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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Cholinergic-associated loss of ...... and cognitive function in mice

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Cholinergic-associated loss of ...... and cognitive function in mice

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Cholinergic-associated loss of ...... and cognitive function in mice

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Cholinergic-associated loss of ...... and cognitive function in mice

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Cholinergic-associated loss of ...... and cognitive function in mice

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Cholinergic-associated loss of ...... and cognitive function in mice

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Cholinergic-associated loss of ...... and cognitive function in mice

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Albert J Becker

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Alon Friedman

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David S Greenberg

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Galit Shaltiel

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Yael Goll

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P2860

Alzheimer's Disease

Acetylcholinesterase--new roles for an old actor

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production

Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

Mutational analysis of a heterogeneous nuclear ribonucleoprotein A2 response element for RNA trafficking

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

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730-742

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254269

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10.1002/EMMM.201100995

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8

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22628224

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Alzheimer's disease

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3494073

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