Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome
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Genomic organization and chromosomal localization of the gene encoding human P-selectin glycoprotein ligandStructure of the human sialophorin (CD43) gene. Identification of features atypical of genes encoding integral membrane proteinsAmino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin)CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytesT cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activationThe scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome.Evidence implicating calpain (Ca(2+)-dependent neutral protease) in the destructive thrombocytopenia of the Wiskott-Aldrich syndrome.Wiskott Aldrich syndrome: an immunodeficiency syndrome not rare in Western Australia.CD43 gene expression is mediated by a nuclear factor which binds pyrimidine-rich single-stranded DNA.Characterization of Two Novel mAbs Recognizing Different Epitopes on CD43.Disregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival.Germ-line mosaicism simulates genetic heterogeneity in Wiskott-Aldrich syndrome.Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation culturesSignaling through CD43 regulates CD4 T-cell traffickingResolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrowT cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome.Altered glycosylation of leukosialin, CD43, in HIV-1-infected cells of the CEM lineIdentification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cellsUse of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome.Wiskott-Aldrich syndrome: a multidisciplinary diseaseHigh salt promotes autoimmunity by TET2-induced DNA demethylation and driving the differentiation of Tfh cells.CD43 interferes with T-lymphocyte adhesion.Intracellular patterns of sialophorin expression define a new molecular classification of breast cancer and represent new targets for therapy.Aberrant glycosylation as biomarker for cancer: focus on CD43.Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules.Carbohydrate-mediated phagocytic recognition of early apoptotic cells undergoing transient capping of CD43 glycoprotein.Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells.CD43 in the nucleus and cytoplasm of lung cancer is a potential therapeutic target.CD43 promotes cell growth and helps to evade FAS-mediated apoptosis in non-hematopoietic cancer cells lacking the tumor suppressors p53 or ARF.The nucleotide sequence of Ly 48 (mouse leukosialin, sialophorin): the mouse homolog of CD43During U937 monocytic differentiation repression of the CD43 gene promoter is mediated by the single-stranded DNA binding protein Pur alpha.The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylationMolecular characterization of gp40, a mucin-type glycoprotein from the apical plasma membrane of Madin-Darby canine kidney cells (type I)Leukosialin (CD43)-major histocompatibility class I molecule interactions involved in spontaneous T cell conjugate formation.Expression of the leukocyte-associated sialoglycoprotein CD43 by a colon carcinoma cell line.The cleavage of neutrophil leukosialin (CD43) by cathepsin G releases its extracellular domain and triggers its intramembrane proteolysis by presenilin/gamma-secretase.CD43 regulates the threshold for T cell activation by targeting Cbl functions.T cell aggregation induced through CD43: intracellular signals and inhibition by the immunomodulatory drug leflunomide.Expression of CD40 and CD43 during activation of human B lymphocytes.Distinct signaling pathways are involved in leukosialin (CD43) down-regulation, membrane blebbing, and phospholipid scrambling during neutrophil apoptosis.
P2860
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P2860
Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
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Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@en
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@nl
type
label
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@ast
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@en
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@nl
prefLabel
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@ast
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@en
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@nl
P2093
P2860
P3181
P356
P1476
Molecular characterization of ...... ve in Wiskott-Aldrich syndrome
@en
P2093
A S Whitehead
C S Shelley
E Remold-O'Donnell
M C Carroll
P2860
P304
P3181
P356
10.1073/PNAS.86.8.2819
P407
P577
1989-04-01T00:00:00Z