A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression - Wikidata - wikimedia - TriplyDB

A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression

A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression

http://www.wikidata.org/entity/Q24620388

about

Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease Mouse models of polyglutamine diseases: review and data table. Part I Natural antisense transcripts Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models A fully humanized transgenic mouse model of Huntington disease.Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.Oligonucleotide-based strategies to combat polyglutamine diseases.Regulatory Roles of Long Non-Coding RNAs in the Central Nervous System and Associated Neurodegenerative Diseases A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.Diced triplets expose neurons to RISC.C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia: gain or loss of function?Brain, blood, and iron: perspectives on the roles of erythrocytes and iron in neurodegeneration.Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice Nucleotide excision repair, mismatch repair, and R-loops modulate convergent transcription-induced cell death and repeat instability Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity.Natural antisense transcripts as therapeutic targets A pathophysiological view of the long non-coding RNA world.Making (anti-) sense out of huntingtin levels in Huntington disease.Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65 Identification of long non-coding transcripts with feature selection: a comparative study.Polyglutamine (polyQ) disorders: the chromatin connection.Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models.RAN Translation in Huntington Disease.Long non-coding RNAs in corticogenesis: deciphering the non-coding code of the brain Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy.RNA toxicity in polyglutamine disorders: concepts, models, and progress of research Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases.Bidirectional transcription of trinucleotide repeats: roles for excision repair.Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome.Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.Exploring cells with targeted biosensors Trojan triplets: RNA-based pathomechanisms for muscle dysfunction in Huntington's disease.Interplay of chromatin modifications and non-coding RNAs in the heart Developmental pruning of excitatory synaptic inputs to parvalbumin interneurons in monkey prefrontal cortex.Consensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias.Asymmetric localization of natural antisense RNA of neuropeptide sensorin in Aplysia sensory neurons during aging and activity.Mechanisms of toxicity in C9FTLD/ALS.Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.

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P2860

A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression

http://www.wikidata.org/entity/Q24620388

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

@wuu

name

A natural antisense transcript ...... locus regulates HTT expression

@ast

A natural antisense transcript ...... locus regulates HTT expression

@en

A natural antisense transcript ...... locus regulates HTT expression

@nl

type

label

A natural antisense transcript ...... locus regulates HTT expression

@ast

A natural antisense transcript ...... locus regulates HTT expression

@en

A natural antisense transcript ...... locus regulates HTT expression

@nl

prefLabel

A natural antisense transcript ...... locus regulates HTT expression

@ast

A natural antisense transcript ...... locus regulates HTT expression

@en

A natural antisense transcript ...... locus regulates HTT expression

@nl

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Human Molecular Genetics

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A natural antisense transcript ...... locus regulates HTT expression

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P2093

Daniel W Chung

http://www.w3.org/2001/XMLSchema#string

Dobrila D Rudnicki

http://www.w3.org/2001/XMLSchema#string

Lan Yu

http://www.w3.org/2001/XMLSchema#string

Russell L Margolis

http://www.w3.org/2001/XMLSchema#string

P2860

A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome

Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene

Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

CTCF: master weaver of the genome

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

CDD: specific functional annotation with the Conserved Domain Database

The transcriptional landscape of the mammalian genome

Protein aggregation and neurodegenerative disease

MatInspector and beyond: promoter analysis based on transcription factor binding sites

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3467-77

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scholarly article

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1638803

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10.1093/HMG/DDR263

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17

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20

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2011-09-01T00:00:00Z

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51218950

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21672921

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Huntington disease

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3153309

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