Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
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Receptor-mediated endocytosis: insights from the lipoprotein receptor systemLow-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasisReduction in cholesterol and low density lipoprotein synthesis after portacaval shunt surgery in a patient with homozygous familial hypercholesterolemiaAccelerating scientific publication in biologyInteraction between Glucose and Lipid Metabolism: More than Diabetic DyslipidemiaHepatitis C Virus entry: the early steps in the viral replication cycleA century of cholesterol and coronaries: from plaques to genes to statinsThematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemiaConversion of low density lipoprotein-associated phosphatidylcholine to triacylglycerol by primary hepatocytesDeletion of PREPl causes growth impairment and hypotonia in miceMetabolism of cationized lipoproteins by human fibroblasts. Biochemical and morphologic correlationsMonogenic disorders.A historical perspective on the discovery of statins.Altered cholesterol trafficking in herpesvirus-infected arterial cells. Evidence for viral protein kinase-mediated cholesterol accumulation.Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteinsRole of conflict of interest in scientific objectivity: a case of a Nobel Prize work.Metabolism of low-density lipoproteins by cultured hepatocytes from normal and homozygous familial hypercholesterolemic subjects.Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts.Human LDL core cholesterol ester packing: three-dimensional image reconstruction and SAXS simulation studiesProprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1)Role of an intramolecular contact on lipoprotein uptake by the LDL receptorLocalization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygoteEvidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of ratDegradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.The genetics of familial hypercholesterolemia and emerging therapiesSolubilization of apolipoprotein B and its specific binding by the cellular receptor for low density lipoprotein.Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor.Receptor-dependent hydrolysis of cholesteryl esters contained in plasma low density lipoprotein.Genetic polymorphisms and lipoprotein responses to diets.Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemiaGenetic diagnosis of familial hypercholesterolaemia by targeted next-generation sequencing.Colloidal gold--low density lipoprotein conjugates as membrane receptor probes.Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo.Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors.Inhibition of lymphoproliferation by hyperlipoproteinemic plasma.Regulation of low density lipoprotein receptor activity in freshly isolated human lymphocytes.Binding, internalization, and degradation of low density lipoprotein by normal human fibroblasts and by fibroblasts from a case of homozygous familial hypercholesterolemiaReceptor-mediated uptake of low density lipoprotein reconstituted with 25-hydroxycholesteryl oleate suppresses 3-hydroxy-3-methylglutaryl-coenzyme A reductase and inhibits growth of human fibroblasts.Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia.Difference in saturable binding of low density lipoprotein to liver membranes from normocholesterolemic subjects and patients with heterozygous familial hypercholesterolemia
P2860
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P2860
Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
description
1974 nî lūn-bûn
@nan
1974 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1974 թվականի մարտին հրատարակված գիտական հոդված
@hy
1974年の論文
@ja
1974年論文
@yue
1974年論文
@zh-hant
1974年論文
@zh-hk
1974年論文
@zh-mo
1974年論文
@zh-tw
1974年论文
@wuu
name
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@ast
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@en
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@nl
type
label
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@ast
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@en
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@nl
prefLabel
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@ast
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@en
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@nl
P2860
P356
P1476
Familial hypercholesterolemia: ...... coenzyme A reductase activity
@en
P2093
J L Goldstein
P2860
P304
P356
10.1073/PNAS.71.3.788
P407
P577
1974-03-01T00:00:00Z