Molecular and cellular pathobiology of Ehrlichia infection: targets for new therapeutics and immunomodulation strategies
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Hacker within! Ehrlichia chaffeensis Effector Driven Phagocyte Reprogramming StrategyThe role of CD8 T lymphocytes in rickettsial infectionsNew insight into immunity and immunopathology of Rickettsial diseasesEhrlichia chaffeensis exploits host SUMOylation pathways to mediate effector-host interactions and promote intracellular survival.Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism.Tyrosine-phosphorylated Ehrlichia chaffeensis and Ehrlichia canis tandem repeat orthologs contain a major continuous cross-reactive antibody epitope in lysine-rich repeats.Ehrlichia chaffeensis TRP120 interacts with a diverse array of eukaryotic proteins involved in transcription, signaling, and cytoskeleton organization.Ehrlichia chaffeensis TRP120 binds a G+C-rich motif in host cell DNA and exhibits eukaryotic transcriptional activator function.Mutations in Ehrlichia chaffeensis Causing Polar Effects in Gene Expression and Differential Host SpecificitiesAttenuated Mutants of Ehrlichia chaffeensis Induce Protection against Wild-Type Infection Challenge in the Reservoir Host and in an Incidental Host.Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survivalEhrlichia chaffeensis Exploits Canonical and Noncanonical Host Wnt Signaling Pathways To Stimulate Phagocytosis and Promote Intracellular SurvivalEhrlichia chaffeensis TRP120 Activates Canonical Notch Signaling To Downregulate TLR2/4 Expression and Promote Intracellular Survival.Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte.Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis.Complete Genome Sequence of Ehrlichia muris Strain AS145T, a Model Monocytotropic Ehrlichia Strain.Ehrlichia chaffeensis TRP32 is a Nucleomodulin that Directly Regulates Expression of Host Genes Governing Differentiation and Proliferation.Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival.Genetic diversity of Ehrlichia canis strains from naturally infected dogs in Rio de Janeiro, Brazil.Ehrlichia chaffeensis TRP120 effector targets and recruits host polycomb group proteins for degradation to promote intracellular infection.Complete Genome Sequence of Ehrlichia canis Strain YZ-1, Isolated from a Beagle with Fever and Thrombocytopenia.
P2860
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P2860
Molecular and cellular pathobiology of Ehrlichia infection: targets for new therapeutics and immunomodulation strategies
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
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2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Molecular and cellular pathobi ...... nd immunomodulation strategies
@ast
Molecular and cellular pathobi ...... nd immunomodulation strategies
@en
Molecular and cellular pathobi ...... nd immunomodulation strategies
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type
label
Molecular and cellular pathobi ...... nd immunomodulation strategies
@ast
Molecular and cellular pathobi ...... nd immunomodulation strategies
@en
Molecular and cellular pathobi ...... nd immunomodulation strategies
@nl
prefLabel
Molecular and cellular pathobi ...... nd immunomodulation strategies
@ast
Molecular and cellular pathobi ...... nd immunomodulation strategies
@en
Molecular and cellular pathobi ...... nd immunomodulation strategies
@nl
P2860
P3181
P1476
Molecular and cellular pathobi ...... nd immunomodulation strategies
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P2093
David H Walker
Jere W McBride
P2860
P3181
P356
10.1017/S1462399410001730
P407
P577
2011-01-01T00:00:00Z