Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera
about
Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen.Congenital platelet disorders and understanding of platelet function.von Willebrand factor, Jedi knight of the bloodstreamTransmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex.The organizing principle of the platelet glycoprotein Ib-IX-V complex.Identification of a juxtamembrane mechanosensitive domain in the platelet mechanosensor glycoprotein Ib-IX complex.Fusion-protein-assisted protein crystallizationThe Transmembrane Domains of β and IX Subunits Mediate the Localization of the Platelet Glycoprotein Ib-IX Complex to the Glycosphingolipid-enriched Membrane DomainStructural basis for the specific inhibition of glycoprotein Ibα shedding by an inhibitory antibodyPlatelet clearance via shear-induced unfolding of a membrane mechanoreceptor.Specific inhibition of ectodomain shedding of glycoprotein Ibα by targeting its juxtamembrane shedding cleavage site.Spectrum of the mutations in Bernard-Soulier syndrome.Rare variants in GP1BB are responsible for autosomal dominant macrothrombocytopenia.Analysis of inter-subunit contacts reveals the structural malleability of extracellular domains in platelet glycoprotein Ib-IX complex.Reconstitution of the platelet glycoprotein Ib-IX complex in phospholipid bilayer Nanodiscs.Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets.Receptor-mediated cell mechanosensing.Two novel variants of uncertain significance in GP9 associated with Bernard-Soulier syndrome: Are they true mutations?
P2860
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P2860
Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera
description
2011 nî lūn-bûn
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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@ast
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@en
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@nl
type
label
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@ast
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@en
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@nl
altLabel
Quaternary organization of GPI ...... GPIb and a GPIb /GPIX chimera
@en
Quaternary organization of GPI ...... GPIb and a GPIb /GPIX chimera
@en
prefLabel
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@ast
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@en
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@nl
P2093
P2860
P3181
P1433
P1476
Quaternary organization of GPI ...... GPIbβ and a GPIbβ/GPIX chimera
@en
P2093
Jonas Emsley
Katherine H Carr
Paul A McEwan
Wenjun Yang
Xiaofeng Zheng
P2860
P304
P3181
P356
10.1182/BLOOD-2011-05-356253
P407
P50
P577
2011-11-10T00:00:00Z