about
Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain TumorigenesisA phosphodiesterase 4B-dependent interplay between tumor cells and the microenvironment regulates angiogenesis in B-cell lymphoma.Psychiatric aspects of phosphodiesterases: An overview.Drotaverine - a Concealed Cytostatic!Cyclic AMP, protein kinase A, and phosphodiesterases: proceedings of an international workshopPDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cellsThe G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastomaChronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (α-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cellsAn in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibitionMechanism of RAF isoform switching induced by oncogenic RAS in melanoma.Targeting brain tumor cAMP: the case for sex-specific therapeuticsPhosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatmentBenzoquinones and terphenyl compounds as phosphodiesterase-4B inhibitors from a fungus of the order Chaetothyriales (MSX 47445).The G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis.Intersections at the crossroads: Neurofibromatosis type 1, cAMP, sex, and glioma risk.Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis.Theobromine, the primary methylxanthine found in Theobroma cacao, prevents malignant glioblastoma proliferation by negatively regulating phosphodiesterase-4, extracellular signal-regulated kinase, Akt/mammalian target of rapamycin kinase, and nucleaDevelopment of anticancer agents targeting the Hedgehog signaling.Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model.Vinpocetine inhibits breast cancer cells growth in vitro and in vivo.Targeted activation of PKA and Epac promotes glioblastoma regression in vitroG-Protein Gαs controls medulloblastoma initiation by suppressing sonic hedgehog signalingThe Role of Protein Kinase B Signaling Pathway in Anti-Cancer Effect of Rolipram on Glioblastoma Multiforme: An In Vitro Study.Quo natas, Danio?—Recent Progress in Modeling Cancer in Zebrafish.Quo natas, Danio?-Recent Progress in Modeling Cancer in Zebrafish.Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Treating brain tumors with PDE4 inhibitors
@ast
Treating brain tumors with PDE4 inhibitors
@en
Treating brain tumors with PDE4 inhibitors
@nl
type
label
Treating brain tumors with PDE4 inhibitors
@ast
Treating brain tumors with PDE4 inhibitors
@en
Treating brain tumors with PDE4 inhibitors
@nl
prefLabel
Treating brain tumors with PDE4 inhibitors
@ast
Treating brain tumors with PDE4 inhibitors
@en
Treating brain tumors with PDE4 inhibitors
@nl
P2093
P2860
P1476
Treating brain tumors with PDE4 inhibitors
@en
P2093
Joshua B Rubin
Nicole M Warrington
Rajarshi Sengupta
P2860
P304
P356
10.1016/J.TIPS.2011.02.015
P407
P577
2011-06-01T00:00:00Z