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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

BST-2/tetherin: a new component of the innate immune response to enveloped viruses

http://www.wikidata.org/entity/Q24630382

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Origins of HIV and the AIDS pandemic BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1 How SAMHD1 changes our view of viral restriction Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS Viral Membrane Channels: Role and Function in the Virus Life Cycle Targeted therapy for HM1.24 (CD317) on multiple myeloma cells Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release Mechanism of HIV-1 virion entrapment by tetherin Anti-inflammatory and anti-remodelling effects of ISU201, a modified form of the extracellular domain of human BST2, in experimental models of asthma: association with inhibition of histone acetylation Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses Intrinsic cellular defenses against human immunodeficiency viruses Two-stepping through time: mammals and viruses Intrinsic antiviral immunity Counteraction of tetherin antiviral activity by two closely related SIVs differing by the presence of a Vpu gene Vpu and BST2: Still Not There Yet?Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion release Maturation and vesicle-mediated egress of primate gammaherpesvirus rhesus monkey rhadinovirus require inner tegument protein ORF52.Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir.Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses.Identification and functional analysis of three isoforms of bovine BST-2 Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity.Characterization of E3 ligases involved in lysosomal sorting of the HIV-1 restriction factor BST2.Interferon-inducible effector mechanisms in cell-autonomous immunity.The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.Association of BST-2 gene variants with HIV disease progression underscores the role of BST-2 in HIV type 1 infection.Antagonism to human BST-2/tetherin by Sendai virus glycoproteins.Influenza A virus does not encode a tetherin antagonist with Vpu-like activity and induces IFN-dependent tetherin expression in infected cells The presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentiviruses Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis.Candida albicans delays HIV-1 replication in macrophages.Feline tetherin efficiently restricts release of feline immunodeficiency virus but not spreading of infection.In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans.

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

http://www.wikidata.org/entity/Q24630382

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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J.TIM.2010.06.010

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Trends in Microbiology

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BST-2/tetherin: a new component of the innate immune response to enveloped viruses

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David T Evans

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John C Guatelli

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Rajendra K Singh

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Ruth Serra-Moreno

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P2860

HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

Initial sequence of the chimpanzee genome and comparison with the human genome

Chimpanzee reservoirs of pandemic and nonpandemic HIV-1

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

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1272854

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10.1016/J.TIM.2010.06.010

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9

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18

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2010-09-01T00:00:00Z

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45507919

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20688520

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2956607

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