Large-scale adeno-associated viral vector production using a herpesvirus-based system enables manufacturing for clinical studies - Wikidata - wikimedia - TriplyDB

Large-scale adeno-associated viral vector production using a herpesvirus-based system enables manufacturing for clinical studies

Large-scale adeno-associated viral vector production using a herpesvirus-based system enables manufacturing for clinical studies

http://www.wikidata.org/entity/Q24630417

about

Manufacturing of recombinant adeno-associated viral vectors for clinical trials Parkinson's disease gene therapy: success by design meets failure by efficacy Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transfer.The potential of adeno-associated viral vectors for gene delivery to muscle tissue.Adeno-associated virus: a key to the human genome?Good manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trial Systemic elimination of de novo capsid protein synthesis from replication-competent AAV contamination in the liver AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities.Self-complementary adeno-associated viral vectors for gene therapy of hemophilia B: progress and challenges Recombinant adeno-associated viral vector production and purification.A Regulatory Element Near the 3' End of the Adeno-Associated Virus rep Gene Inhibits Adenovirus Replication in cis by Means of p40 Promoter-Associated Short Transcripts.A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy Recombinant adeno-associated virus vectors in the treatment of rare diseases.OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy Gene therapy for the treatment of chronic peripheral nervous system pain.In situ production of therapeutic monoclonal antibodies.Peptide affinity reagents for AAV capsid recognition and purification A Preclinical Study in Rhesus Macaques for Cystic Fibrosis to Assess Gene Transfer and Transduction by AAV1 and AAV5 with a Dual-Luciferase Reporter System.Adeno-Associated Virus Gene Therapy for Liver Disease.Polymeric nanoparticles as cancer-specific DNA delivery vectors to human hepatocellular carcinoma.Copackaging of multiple adeno-associated viral vectors in a single production step.Manufacturing of recombinant adeno-associated viruses using mammalian expression platforms.Production and discovery of novel recombinant adeno-associated viral vectors.Analysis of particle content of recombinant adeno-associated virus serotype 8 vectors by ion-exchange chromatography.Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.A versatile adeno-associated virus vector producer cell line method for scalable vector production of different serotypes.The liver as a target organ for gene therapy: state of the art, challenges, and future perspectives.Clearance and characterization of residual HSV DNA in recombinant adeno-associated virus produced by an HSV complementation system.Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector A scalable method for the production of high-titer and high-quality adeno-associated type 9 vectors using the HSV platform.Adeno-Associated Virus (AAV) gene therapy for cystic fibrosis: current barriers and recent developments.Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection.Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.Molecular design for recombinant adeno-associated virus (rAAV) vector production.Gene Therapy for Autoimmune Disease.A Recombinant Baculovirus Efficiently Generates Recombinant Adeno-Associated Virus Vectors in Cultured Insect Cells and Larvae.Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes

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P2860

Large-scale adeno-associated viral vector production using a herpesvirus-based system enables manufacturing for clinical studies

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2009 nî lūn-bûn

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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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Human Gene Therapy

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Barry J Byrne

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David R Knop

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Nathalie Clément

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P2860

Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use.

Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.

Adeno-associated virus DNA replication complexes in herpes simplex virus or adenovirus-infected cells.

Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system.

Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.

Production processes of licensed recombinant factor VIII preparations.

Role of the herpes simplex virus helicase-primase complex during adeno-associated virus DNA replication

Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction.

Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells.

Replication-defective genomic HSV gene therapy vectors: design, production and CNS applications.

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796-806

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10.1089/HUM.2009.094

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20

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19569968

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2861951

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