Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2 - Wikidata - wikimedia - TriplyDB

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

http://www.wikidata.org/entity/Q24630870

about

Stable long-term cultures of self-renewing B cells and their applications EZH2 in normal hematopoiesis and hematological malignancies Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling Chromatin targeting drugs in cancer and immunity Epigenetic Modulation as a Therapeutic Prospect for Treatment of Autoimmune Rheumatic Diseases miR290-5p/292-5p activate the immunoglobulin kappa locus in B cell development Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile The natural chemopreventive agent sulforaphane inhibits STAT5 activity Subnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repression Discovering transcription factor regulatory targets using gene expression and binding data Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3.DNA methylation and transcription in a distal region upstream from the bovine AlphaS1 casein gene after once or twice daily milking.Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules Phospholipase C-β in immune cells.The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation.IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.Mechanisms of Jak/STAT signaling in immunity and disease Histone reader BRWD1 targets and restricts recombination to the Igk locus.Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes.The STAT5b Pathway Defect and Autoimmunity G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition.JAK and STAT signaling molecules in immunoregulation and immune-mediated disease.Leptin-STAT3-G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression.IL-7 signalling represses Bcl-6 and the TFH gene program.Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.T follicular helper cell diversity and plasticity Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals Mammary-specific gene activation is defined by progressive recruitment of STAT5 during pregnancy and the establishment of H3K4me3 marks.The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions.Balancing Proliferation with Igκ Recombination during B-lymphopoiesis The role of STAT5 in lymphocyte development and transformation The JAK-STAT pathway at twenty.Immune regulation by phospholipase C-β isoforms.Autoimmunity in 2011.IRF4 and IRF8: Governing the virtues of B Lymphocytes.

P2860

Q26766723-2A989960-1ABF-4BCC-96D6-F6DEC0D1BFCE Q26779821-368902FE-AAE0-44C3-87A2-BA5EA9C3B9BD Q26862927-9FA4ABFF-F099-457C-8C34-6822F76C1E4A Q26999888-AF30EDDE-9B13-44BF-9C78-38EF211B520C Q28079715-BD96EE4C-7D01-46AB-9467-20AEFC90D16E Q28482491-A1B5D06B-D316-458A-B54D-F0AB62D00DE3 Q28508595-94CDCE6D-4065-4900-B99D-77B6B3521896 Q28539573-CA510581-9C0B-4666-A5DA-1E6D927FEDC2 Q28585407-EC8E52F9-9987-41D2-B325-70CA031A7A32 Q34074703-28E31B5C-A6BE-468D-A1E4-889698CC4303 Q34252584-D422B888-7302-425B-98B8-89648C0CD74C Q34450331-71BC84A4-C53C-4F11-901D-2A89EA66AD48 Q34550054-BD37295E-3C30-4A26-A441-53E5ECEA3BAE Q35073385-7B38C92E-BEF0-40D1-99FB-1AB9C5B7F854 Q35111380-6FE063F5-74A4-48E9-8281-C1AD4FAAFED8 Q35141647-85F14CD5-65DA-4AA0-9ED1-1A39FE18BCEF Q35202373-032ACFC7-63A4-4F8E-B0C4-4D8655CDDBFE Q35763391-2BCF6E28-C307-4D97-B4AA-582BBD640C70 Q35915068-A50E1637-4370-4469-9EE2-A85F9DCDBF94 Q36074413-842DE77F-BB1B-453F-AB83-0030A816D399 Q36160621-0E45F655-5996-4998-BFA6-A127C6910F60 Q36162564-2743DE63-DE1A-486B-8289-812079B26220 Q36322506-91456724-6C8B-4D94-A4DD-C36FFFC90622 Q36404704-391CB5B8-2BDB-445B-8304-62E6D960FC3D Q36411081-C96CF5CA-9DDE-487F-8A93-E76F02137144 Q36511197-45045A14-B855-46F6-9B91-8A07DC606776 Q36551220-89396F27-CE17-4D61-BDAE-D532DA92B2E7 Q36567934-3721C80A-52AA-4EA5-AEFC-C51D5CCA3D1B Q36569363-3BAD5413-4911-4428-BDB6-9E8F33BD58F7 Q36823844-57AB7EBC-4463-48CF-87ED-885BF7D347FD Q37323207-5AA384DE-A8D5-4B1E-9A29-508C50E9C60C Q37397804-2B48E0C2-934A-49BD-9759-60C40DFB8F23 Q37546911-2BD230A0-843E-493E-8CA4-44E48CD61CB6 Q37577429-736A2ADD-34B2-4BB6-8CB9-88B067D941D7 Q37692925-8688DF38-D761-46F8-B944-738124627110 Q37985185-88F12EE7-4C35-416B-AA4D-69AC03229642 Q38004201-0305F581-6B58-46EB-8745-35C00E461CC1 Q38013658-0EC4C701-C551-41BD-AB5A-5B2589860E26 Q38021696-78F5CADB-7FCD-48C4-AA9B-63BBFF62E172 Q38288293-8CB2C7CD-E2E8-40B4-A821-E0E5B9F1D7C2

P2860

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

http://www.wikidata.org/entity/Q24630870

description

2011 nî lūn-bûn

@nan

2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@ast

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@en

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@nl

type

label

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@ast

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@en

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@nl

prefLabel

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@ast

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@en

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@nl

P1433

Q24630870-38A121B2-32EA-4652-BABE-F74A1209F467

P1476

Q24630870-C3AAAF2B-2D76-4496-8CFE-4DD789BF1725

P2093

Q24630870-1C905180-87E6-466F-8AE0-19B1F3C73944

Q24630870-39827F98-A406-4828-8F09-1C65C04C5C94

Q24630870-6C1A7412-BF2E-466F-A6B2-4915BFFD3B96

Q24630870-93DC47B8-5F58-4A80-A227-2E3B7A52D75F

Q24630870-9A631DC7-E25A-4301-8ADC-4561881DA25F

Q24630870-9C1928D2-126E-4902-82AD-72C7B17836B5

Q24630870-B863F229-1809-4EB3-B02D-754773107116

Q24630870-F1DF0A98-4415-41E1-B6DE-59776EADB6D1

P2860

Q24630870-07E807AF-AD66-462F-AD3A-C2C315B2DFB3

Q24630870-10EAA3C2-0236-4981-BF5F-A6A54EDFF74E

Q24630870-1939A24D-8735-4704-B714-91DFAE2E4E3C

Q24630870-19C4CEF9-A589-432E-B6A0-E19896A76E15

Q24630870-1BB74A56-3522-4CBC-A7E7-01EAF096CDF7

Q24630870-2306A155-ADB0-4619-A80B-7807A085C7F5

Q24630870-2692604B-AB15-48A3-89D5-44EA23BA3087

Q24630870-2E03F43C-C2A3-4222-9F81-9B07B84E82B9

Q24630870-2EEF222B-5B3E-4C2B-B107-E5AD8B9C07FF

Q24630870-31A8FD11-7D6E-4B79-8B49-44E74A8460B4

P2888

Q24630870-E91D3677-4609-4596-BAB5-4521FC706C4B

P304

Q24630870-AD2A3C5B-AEE6-412A-B970-946E3C1380B2

P31

Q24630870-A2CC1DCE-596B-48C5-BB2B-90EACFD3E58A

P3181

Q24630870-3B5CA3AC-0C0B-42B3-8430-42E02160E0B4

P356

Q24630870-CB92213D-7B13-4146-B26B-FD1A7174D852

P407

Q24630870-ED8392C2-01B2-4598-874A-633EA8E15788

P433

Q24630870-5E31385C-0540-4AC9-9298-90AB8037CEF2

P478

Q24630870-2FF89561-D81D-4A88-A40C-E92D6752034A

P577

Q24630870-076515C1-F54F-45CB-A9D8-9360ED494AA2

P5875

Q24630870-83D4C93E-FF8E-4E02-9FEE-998A3D88C6C1

P6179

Q24630870-C151B34A-0A7A-43AE-9696-B5C7230A9B82

P698

Q24630870-E26CC4FE-DA8F-47DE-9BF6-B5079EBD3ACB

P932

Q24630870-3673B66A-AE32-4609-B0B6-13ED95575C7D

P3181

P356

P1433

Nature Immunology

P1476

Epigenetic repression of the I ...... histone methyltransferase Ezh2

@en

P2093

Aaron R Dinner

http://www.w3.org/2001/XMLSchema#string

Barbara L Kee

http://www.w3.org/2001/XMLSchema#string

Elizabeth T Bartom

http://www.w3.org/2001/XMLSchema#string

Keith M Hamel

http://www.w3.org/2001/XMLSchema#string

Malay Mandal

http://www.w3.org/2001/XMLSchema#string

Marcus R Clark

http://www.w3.org/2001/XMLSchema#string

Mark Maienschein-Cline

http://www.w3.org/2001/XMLSchema#string

Sarah E Powers

http://www.w3.org/2001/XMLSchema#string

P2860

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells.

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Histone modifications at human enhancers reflect global cell-type-specific gene expression

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

Functional interactions between Stat5 and the glucocorticoid receptor

Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo

B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta

DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites

The Polycomb complex PRC2 and its mark in life

P2888

P304

1212-20

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3370318

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NI.2136

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P577

2011-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51752313

http://www.w3.org/2001/XMLSchema#string

P6179

1007726488

http://www.w3.org/2001/XMLSchema#string

P698

22037603

http://www.w3.org/2001/XMLSchema#string

P932

3233979

http://www.w3.org/2001/XMLSchema#string