GEF what? Dock180 and related proteins help Rac to polarize cells in new ways - Wikidata - wikimedia - TriplyDB

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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Rac and Rho GTPases in cancer cell motility control DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation Comparative Anatomy of Phagocytic and Immunological Synapses Regulation of small GTPases by GEFs, GAPs, and GDIs Function and regulation of the Rho guanine nucleotide exchange factor Trio Capping protein regulators fine-tune actin assembly dynamics Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells The DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS development Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (DOCK) Nucleotide Exchange Factors Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms Experimental Diabetes Mellitus in Different Animal Models Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal Degeneration DOCK5 and DOCK1 regulate Caco-2 intestinal epithelial cell spreading and migration on collagen IV Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling Recessive mutations in DOCK6, encoding the guanidine nucleotide exchange factor DOCK6, lead to abnormal actin cytoskeleton organization and Adams-Oliver syndrome The Hyper-IgE Syndromes: Lessons in Nature, From Bench to Bedside DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory The RhoGEF DOCK10 is essential for dendritic spine morphogenesis Cell adhesion: integrating cytoskeletal dynamics and cellular tension.Dedicator of Cytokinesis 2 in Cell Signaling Regulation and Disease Development.The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif.The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration.Breast cancer anti-estrogen resistance 3 (BCAR3) protein augments binding of the c-Src SH3 domain to Crk-associated substrate (p130cas)The Dynamics of Apoptotic Cell Clearance Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.Integrin-linked kinase interactions with ELMO2 modulate cell polarity Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility.Visualization of Src activity at different compartments of the plasma membrane by FRET imaging.Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function Asymmetric Mbc, active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions An Elmo-Dock complex locally controls Rho GTPases and actin remodeling during cadherin-mediated adhesion

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

http://www.wikidata.org/entity/Q24633334

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2007 nî lūn-bûn

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2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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prefLabel

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

@ast

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

@en

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

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P1433

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P356

J.TCB.2007.05.001

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Trends in Cell Biology

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GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

@en

P2093

Jean-François Côté

http://www.w3.org/2001/XMLSchema#string

Kristiina Vuori

http://www.w3.org/2001/XMLSchema#string

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Activation of Rac1 by a Crk SH3-binding protein, DOCK180

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1

PH domain of ELMO functions in trans to regulate Rac activation via Dock180

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3

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383-93

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scholarly article

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824816

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10.1016/J.TCB.2007.05.001

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8

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17

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2007-08-01T00:00:00Z

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6074006

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17765544

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P932

2887429

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