Rates and fitness consequences of new mutations in humans
about
The case for junk DNADefining functional DNA elements in the human genomeMale-mediated developmental toxicityRate of de novo mutations and the importance of father's age to disease riskBackground selection 20 years on: the Wilhelmine E. Key 2012 invitational lectureEpigenetic reduction of DNA repair in progression to gastrointestinal cancerMutation and Human Exceptionalism: Our Future Genetic LoadDirect estimate of the rate of germline mutation in a birdAs it happens: current directions in experimental evolutionNANOGP8: evolution of a human-specific retro-oncogeneEvolutionary shaping of demographic schedules.Genetic diversity in migratory bats: Results from RADseq data for three tree bat species at an Ohio windfarmInference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data.Whole exome sequencing to identify genetic causes of short statureMissing heritability of common diseases and treatments outside the protein-coding exome.A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus.The impact of whole-genome sequencing on the reconstruction of human population history.8-oxoguanine causes spontaneous de novo germline mutations in mice.A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness.The effect of paternal age on offspring intelligence and personality when controlling for paternal trait levelBy their words ye shall know them: Evidence of genetic selection against general intelligence and concurrent environmental enrichment in vocabulary usage since the mid 19th century.The effects of deleterious mutations on evolution at linked sitesFitness Consequences of Advanced Ancestral Age over Three Generations in Humans.Time-dependent estimates of molecular evolutionary rates: evidence and causes.The evolution of obligate sex: the roles of sexual selection and recombination.Effects of Interference Between Selected Loci on the Mutation Load, Inbreeding Depression, and Heterosis.Sex-Specific Selection and Sex-Biased Gene Expression in Humans and Flies.Drift load in populations of small size and low densityMutation load under additive fitness effects.Population growth inflates the per-individual number of deleterious mutations and reduces their mean effect.Estimation of the spontaneous mutation rate per nucleotide site in a Drosophila melanogaster full-sib family.Population genetics from 1966 to 2016.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.The disparity mutagenesis model predicts rescue of living things from catastrophic errors.Mutation rates for 20 STR loci in a population from São Paulo state, Southeast, Brazil.Hermann Muller on Measuring Mutation Rates.Evaluation of chemical mutagenicity using next generation sequencing: A review.The double edged sword: The demographic consequences of the evolution of self-fertilization.Paternal age bioethics.A comparison of models to infer the distribution of fitness effects of new mutations.
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P2860
Rates and fitness consequences of new mutations in humans
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Rates and fitness consequences of new mutations in humans
@ast
Rates and fitness consequences of new mutations in humans
@en
Rates and fitness consequences of new mutations in humans
@nl
type
label
Rates and fitness consequences of new mutations in humans
@ast
Rates and fitness consequences of new mutations in humans
@en
Rates and fitness consequences of new mutations in humans
@nl
prefLabel
Rates and fitness consequences of new mutations in humans
@ast
Rates and fitness consequences of new mutations in humans
@en
Rates and fitness consequences of new mutations in humans
@nl
P2860
P3181
P1433
P1476
Rates and fitness consequences of new mutations in humans
@en
P2093
Peter D Keightley
P2860
P304
P3181
P356
10.1534/GENETICS.111.134668
P407
P577
2012-02-01T00:00:00Z