Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
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Whole exome sequencing identifies new causative mutations in Tunisian families with non-syndromic deafnessThe evolutionary and genetic origins of consciousness in the Cambrian Period over 500 million years agoTMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner earIs TMC1 the Hair Cell Mechanotransducer Channel?Touch sense: functional organization and molecular determinants of mechanosensitive receptorsMechanosensory molecules and circuits in C. elegansGenetics of hearing and deafnessExome sequencing identifies a mutation in TMC1 as a novel cause of autosomal recessive nonsyndromic hearing lossThe effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cellsMechanically Activated Ion ChannelsA Novel C-Terminal CIB2 (Calcium and Integrin Binding Protein 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic FamilyLoss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephoneIntegrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death.Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2Mechanotransduction as an Adaptation to Gravity.Conductance and block of hair-cell mechanotransducer channels in transmembrane channel-like protein mutantsTMHS is an integral component of the mechanotransduction machinery of cochlear hair cellsDeficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in miceCharacterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factorTmc gene therapy restores auditory function in deaf mice.Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.The physiology of mechanoelectrical transduction channels in hearing.Permeation of fluorophore-conjugated phalloidin into live hair cells of the inner ear is modulated by P2Y receptors.TMC function in hair cell transductionLocal mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells.Genetics of auditory mechano-electrical transduction.Sound strategies for hearing restoration.Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochleaDevelopmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel-like proteins.Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cellsHow we feel: ion channel partnerships that detect mechanical inputs and give rise to touch and pain perceptionTRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells.Using injectoporation to deliver genes to mechanosensory hair cellsDesigner aminoglycosides prevent cochlear hair cell loss and hearing lossSubunit determination of the conductance of hair-cell mechanotransducer channelsTransmembrane channel-like (tmc) gene regulates Drosophila larval locomotion.Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.
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P2860
Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
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2011 nî lūn-bûn
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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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Mechanotransduction in mouse i ...... ansmembrane channel-like genes
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Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
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Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
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Mechanotransduction in mouse i ...... ansmembrane channel-like genes
@nl
Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
@ast
Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
@en
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Mechanotransduction in mouse i ...... ansmembrane channel-like genes
@nl
Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
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Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
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P2093
P2860
P921
P3181
P356
P1476
Mechanotransduction in mouse i ...... nsmembrane channel-like genes.
@en
P2093
Andrea Lelli
Andrew J Griffith
Charles C Della Santina
Doris K Wu
Gwenaëlle S G Géléoc
Jeffrey R Holt
Kiyoto Kurima
Tomoko Makishima
Valentina Labay
Yoshiyuki Kawashima
P2860
P304
P3181
P356
10.1172/JCI60405
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P577
2011-11-21T00:00:00Z