Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS
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Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP functionToward precision medicine in amyotrophic lateral sclerosisInhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes.Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.3'UTRs take a long shot in the brain.The future of blood-based biomarkers for Alzheimer's disease.Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS)Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS.A Comprehensive Profile of ChIP-Seq-Based Olig2 Target Genes in Motor Neuron Progenitor Cells Suggests the Possible Involvement of Olig2 in the Pathogenesis of Amyotrophic Lateral Sclerosis.Will posttranslational modifications of brain proteins provide novel serological markers for dementias?Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro.The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease.TDP-43 pathology in polyglutamine diseases: with reference to amyotrphic lateral sclerosis.Prion-like propagation as a pathogenic principle in frontotemporal dementia.Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy.Novel FUS mutations identified through molecular screening in a large cohort of familial and sporadic amyotrophic lateral sclerosis.Isoform-specific antibodies reveal distinct subcellular localizations of C9orf72 in amyotrophic lateral sclerosis.RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLDDendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma.Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.Early and selective reduction of NOP56 (Asidan) and RNA processing proteins in the motor neuron of ALS model mice.Truncating mutations in FUS/TLS give rise to a more aggressive ALS-phenotype than missense mutations: a clinico-genetic study in Germany.Biological Spectrum of Amyotrophic Lateral Sclerosis Prions.De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies.RNA binding proteins and the pathological cascade in ALS/FTD neurodegeneration.The roles of intrinsic disorder-based liquid-liquid phase transitions in the "Dr. Jekyll-Mr. Hyde" behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.Causative Genes in Amyotrophic Lateral Sclerosis and Protein Degradation Pathways: a Link to Neurodegeneration.Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice.Autophagy as a common pathway in amyotrophic lateral sclerosis.Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
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P2860
Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@ast
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@en
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@nl
type
label
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@ast
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@en
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@nl
prefLabel
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@ast
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@en
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@nl
P2860
P3181
P1433
P1476
Conjoint pathologic cascades m ...... inding proteins TDP-43 and FUS
@en
P2093
Daisuke Ito
Norihiro Suzuki
P2860
P304
P3181
P356
10.1212/WNL.0B013E3182343365
P407
P577
2011-10-25T00:00:00Z