Flow of information in the light-triggered cyclic nucleotide cascade of vision
about
Human cDNA clones for an alpha subunit of Gi signal-transduction proteinHuman melanopsin forms a pigment maximally sensitive to blue light (λmax ≈ 479 nm) supporting activation of G(q/11) and G(i/o) signalling cascadesPhosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segmentsSpecificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channelcGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunitsBlocking taste receptor activation of gustducin inhibits gustatory responses to bitter compoundsFunctional comparison of RGS9 splice isoforms in a living cellIns and outs of GPCR signaling in primary ciliaLight-activated rhodopsin induces structural binding motif in G protein alpha subunitBeta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identicalIn vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84Interspecies conservation of retinal guanosine 5'-triphosphatase. Characterization by photoaffinity labelling and tryptic-peptide mappingG protein diversity is increased by associations with a variety of gamma subunitsThe GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunitChemistry and biology of the initial steps in vision: the Friedenwald lecture.Rhodopsin: the functional significance of asn-linked glycosylation and other post-translational modifications2-Azido-[32P]NAD+, a photoactivatable probe for G-protein structure: evidence for holotransducin oligomers in which the ADP-ribosylated carboxyl terminus of alpha interacts with both alpha and gamma subunits.The discovery of signal transduction by G proteins: a personal account and an overview of the initial findings and contributions that led to our present understanding.Sensitive light scattering probe of enzymatic processes in retinal rod photoreceptor membranes.Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice.Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. I. Identification of the kinase and its role in the turnoff of phosphodiesterase in vitro.Molecular genetics of retinitis pigmentosaG protein mRNA mapped in rat brain by in situ hybridizationRhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors.Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin.Opsin exhibits cGMP-activated single-channel activity.Molecular mechanisms of go signalingAn estimate of the number of G regulator proteins activated per excited rhodopsin in living Limulus ventral photoreceptors.cGMP is tightly bound to bovine retinal rod phosphodiesteraseComplexes between photoactivated rhodopsin and transducin: progress and questions.The amino terminus of the fourth cytoplasmic loop of rhodopsin modulates rhodopsin-transducin interaction.Surface plasmon resonance spectroscopy studies of membrane proteins: transducin binding and activation by rhodopsin monitored in thin membrane filmsReproducible and sustained regulation of Gαs signalling using a metazoan opsin as an optogenetic toolA structural model for the alpha-subunit of transducin. Implications of its role as a molecular switch in the visual signal transduction mechanism.Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopyThe biochemistry and physiology of metallic fluoride: action, mechanism, and implications.Expression of the functional cone phototransduction cascade in retinoblastomaThe transducin cascade is involved in the light-induced structural changes observed by neutron diffraction on retinal rod outer segmentsDiscovering electrophysiology in photobiology: A brief overview of several photobiological processes with an emphasis on electrophysiology
P2860
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P2860
Flow of information in the light-triggered cyclic nucleotide cascade of vision
description
1981 nî lūn-bûn
@nan
1981 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
name
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@ast
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@en
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@nl
type
label
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@ast
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@en
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@nl
prefLabel
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@ast
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@en
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@nl
P2093
P2860
P356
P1476
Flow of information in the light-triggered cyclic nucleotide cascade of vision
@en
P2093
P2860
P356
10.1073/PNAS.78.1.152
P407
P577
1981-01-01T00:00:00Z