Germline BAP1 mutations predispose to malignant mesothelioma - Wikidata - wikimedia - TriplyDB

Germline BAP1 mutations predispose to malignant mesothelioma

Germline BAP1 mutations predispose to malignant mesothelioma

http://www.wikidata.org/entity/Q24635326

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High incidence of somatic BAP1 alterations in sporadic malignant mesothelioma ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium Hedgehog Signaling in Malignant Pleural Mesothelioma New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas Developmental disease and cancer: biological and clinical overlaps Emerging patterns of somatic mutations in cancer Personalized oncogenomics: clinical experience with malignant peritoneal mesothelioma using whole genome sequencing.Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors.Consensus report of the 2015 Weinman International Conference on Mesothelioma The genetics of uveal melanoma: current insights Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer Connecting molecular pathways to hereditary cancer risk syndromes Cytoplasmic expression of BAP1 as an independent prognostic biomarker for patients with gliomas Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma Loss of expression of BAP1 is a useful adjunct, which strongly supports the diagnosis of mesothelioma in effusion cytology Recent insights emerging from malignant mesothelioma genome sequencing Mithramycin Depletes Specificity Protein 1 and Activates p53 to Mediate Senescence and Apoptosis of Malignant Pleural Mesothelioma Cells Minimal asbestos exposure in germline BAP1 heterozygous mice is associated with deregulated inflammatory response and increased risk of mesothelioma An asbestos-exposed family with multiple cases of pleural malignant mesothelioma without inheritance of a predisposing BAP1 mutation Germline BAP1 mutation in a family with high incidence of multiple primary cancers and a potential gene-environment interaction Current issues in malignant pleural mesothelioma evaluation and management High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma Comprehensive review of BAP1 tumor predisposition syndrome with report of two new cases BAP1 hereditary cancer predisposition syndrome: a case report and review of literature The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms)FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma Modern management of malignant pleural mesothelioma Switching off malignant mesothelioma: exploiting the hypoxic microenvironment Analysis of BAP1 Germline Gene Mutation in Young Uveal Melanoma Patients BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.Establishment and mutation analysis of a novel malignant peritoneal mesothelioma cell line, TU-MM-1, using whole genome sequencing.

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Germline BAP1 mutations predispose to malignant mesothelioma

http://www.wikidata.org/entity/Q24635326

description

2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Germline BAP1 mutations predispose to malignant mesothelioma

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Germline BAP1 mutations predispose to malignant mesothelioma

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Germline BAP1 mutations predispose to malignant mesothelioma

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type

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Germline BAP1 mutations predispose to malignant mesothelioma

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Germline BAP1 mutations predispose to malignant mesothelioma

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Germline BAP1 mutations predispose to malignant mesothelioma

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prefLabel

Germline BAP1 mutations predispose to malignant mesothelioma

@ast

Germline BAP1 mutations predispose to malignant mesothelioma

@en

Germline BAP1 mutations predispose to malignant mesothelioma

@nl

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Nature Genetics

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Germline BAP1 mutations predispose to malignant mesothelioma

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A Umran Dogan

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Amy Powers

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Eleonora Sementino

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Haining Yang

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Jianming Pei

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Joseph R Testa

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Masaki Nasu

http://www.w3.org/2001/XMLSchema#string

Mika Tanji

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Mitchell Cheung

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Sandra Trusa

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P2860

Residential proximity to naturally occurring asbestos and mesothelioma risk in California

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization

Frequent mutation of BAP1 in metastasizing uveal melanomas

A second generation human haplotype map of over 3.1 million SNPs

Diverse mutations in patients with Menkes disease often lead to exon skipping

Splicing in action: assessing disease causing sequence changes

PLINK: a tool set for whole-genome association and population-based linkage analyses

Principal components analysis corrects for stratification in genome-wide association studies

Malignant mesothelioma: facts, myths, and hypotheses

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1022-5

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10.1038/NG.912

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10

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43

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Michele Carbone

Sabahattin Comertpay

Mary Hesdorffer

Giovanni Gaudino

Jennifer Elizabeth Below

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2011-10-01T00:00:00Z

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51602024

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1006344582

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21874000

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