Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance - Wikidata - wikimedia - TriplyDB

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

http://www.wikidata.org/entity/Q24642248

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Store-independent activation of Orai1 by SPCA2 in mammary tumors Human muscle economy myoblast differentiation and excitation-contraction coupling use the same molecular partners, STIM1 and STIM2 STIM proteins: dynamic calcium signal transducers T cell activation T cell receptor signalling in the control of regulatory T cell differentiation and function STIM and Orai1 Variants in Store-Operated Calcium Entry STIM and ORAI proteins in the nervous system Modulation of T Cell Metabolism and Function through Calcium Signaling Nuclear factor of activated T cells - a transcription factor family as critical regulator in lung and colon cancer Ion channels and transporters in lymphocyte function and immunity T-regulatory cells in primary immune deficiencies Store-operated calcium signaling in neutrophils Molecular regulation of CRAC channels and their role in lymphocyte function Multifaceted roles of STIM proteins Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migration The STIM1-Orai1 pathway of store-operated Ca2+ entry controls the checkpoint in cell cycle G1/S transition.Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry Diseases caused by mutations in ORAI1 and STIM1 TMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signaling STIM1 gates the store-operated calcium channel ORAI1 in vitro Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction.Hair loss and defective T- and B-cell function in mice lacking ORAI1 STIMulating store-operated Ca(2+) entry.STIM1 calcium sensor is required for activation of the phagocyte oxidase during inflammation and host defense Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes.The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning.STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome.STIM and Orai isoform expression in pregnant human myometrium: a potential role in calcium signaling during pregnancy.Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance Blocking of stromal interaction molecule 1 expression influence cell proliferation and promote cell apoptosis in vitro and inhibit tumor growth in vivo in head and neck squamous cell carcinoma The landscape of human genes involved in the immune response to parasitic worms ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia.The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.

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Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

http://www.wikidata.org/entity/Q24642248

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Dual functions for the endopla ...... cell activation and tolerance

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Dual functions for the endopla ...... cell activation and tolerance

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Dual functions for the endopla ...... cell activation and tolerance

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Dual functions for the endopla ...... cell activation and tolerance

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Nature Immunology

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Dual functions for the endopla ...... cell activation and tolerance

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Anjana Rao

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Ed Lamperti

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Masatsugu Oh-Hora

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Megumi Yamashita

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Murali Prakriya

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Patrick G Hogan

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Sonia Sharma

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Woo Chung

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The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins

STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry

FOXP3 controls regulatory T cell function through cooperation with NFAT

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

Orai1 is an essential pore subunit of the CRAC channel

STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels

Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

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432-43

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10.1038/NI1574

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4

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9

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2008-04-01T00:00:00Z

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5525493

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1010593683

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18327260

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endoplasmic reticulum

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2737533

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