SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions - Wikidata - wikimedia - TriplyDB

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

http://www.wikidata.org/entity/Q24643366

about

Strategies to overcome antileishmanial drugs unresponsiveness XMetDB: an open access database for xenobiotic metabolism Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin Towards structural systems pharmacology to study complex diseases and personalized medicine Different frequencies of drug resistance mutations among HIV-1 subtypes circulating in China: a comprehensive study Characterization of differences in substrate specificity among CYP1A1, CYP1A2 and CYP1B1: an integrated approach employing molecular docking and molecular dynamics simulations.RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes.CYPSI: a structure-based interface for cytochrome P450s and ligands in Arabidopsis thaliana Improving data and knowledge management to better integrate health care and research.Ivermectin to reduce malaria transmission II. Considerations regarding clinical development pathway Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety Predictors of blood trihalomethane concentrations in NHANES 1999-2006.Machine learning-based prediction of drug-drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes.PubChem applications in drug discovery: a bibliometric analysis Sucralose, a synthetic organochlorine sweetener: overview of biological issues MutaCYP: Classification of missense mutations in human cytochromes P450 A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case.Bioinformatics and variability in drug response: a protein structural perspective.Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy predictions.Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine-Pyrimethamine Disposition Among Ugandan Pregnant Women.Role of Pharmacogenetics in Improving the Safety of Psychiatric Care by Predicting the Potential Risks of Mania in CYP2D6 Poor Metabolizers Diagnosed With Bipolar Disorder Saint John's wort, an herbal inducer of the cytochrome P4503A4 isoform, may alleviate symptoms of Willis-Ekbom's disease.Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma.Informatics confronts drug-drug interactions A service improvement project to review prescribing information provided by general practitioners for new referrals to a UK National Health Service hospital pain clinic: potential implications of CYP2D6 enzyme inhibition.Associations between CYP1A1 rs1048943 A > G and rs4646903 T > C genetic variations and colorectal cancer risk: Proof from 26 case-control studies.The Transformer database: biotransformation of xenobiotics.Cytochrome P450 variations in different ethnic populations.Clinical validity of cytochrome P450 metabolism and serotonin gene variants in psychiatric pharmacotherapy.Complexities of CYP2D6 gene analysis and interpretation.A therapeutic interaction between cimetidine and clozapine: case study and review of the literature.Single nucleotide polymorphism and its dynamics for pharmacogenomics.Drug-drug interaction discovery and demystification using Semantic Web technologies.SuperTarget goes quantitative: update on drug-target interactions.Choosing the safest acute therapy during chronic migraine prophylactic treatment: pharmacokinetic and pharmacodynamic considerations.Pharmacological indices and pulmonary distribution of rifampicin after repeated oral administration in healthy foals.Pharmacogenomics of second-line drugs used for treatment of unresponsive or relapsed osteosarcoma patients.Possible biomarkers modulating haloperidol efficacy and/or tolerability.

P2860

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P2860

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

http://www.wikidata.org/entity/Q24643366

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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SuperCYP: a comprehensive data ...... lysis of CYP-drug interactions

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SuperCYP: a comprehensive data ...... lysis of CYP-drug interactions

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Nucleic Acids Research

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SuperCYP: a comprehensive data ...... lysis of CYP-drug interactions

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Christian Senger

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Daniel Kuzman

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Gady Goldsobel

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Katharina Kroll

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Mathias Dunkel

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P2860

The Protein Data Bank

The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system

The Blue Obelisk-interoperability in chemical informatics

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

Improved mutation tagging with gene identifiers applied to membrane protein stability prediction

Protein Data Bank (PDB): database of three-dimensional structural information of biological macromolecules.

Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. II. In vitro-in vivo correlation with ketoconazole.

The NCBI BioSystems database

Cytochrome P450 enzyme system: genetic polymorphisms and impact on clinical pharmacology.

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D237-43

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scholarly article

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3500876

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10.1093/NAR/GKP970

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Database issue

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38

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Robert Preissner

Michael Schroeder

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2010-01-01T00:00:00Z

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40027605

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19934256

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2808967

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