hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells - Wikidata - wikimedia - TriplyDB

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells

http://www.wikidata.org/entity/Q24643834

about

NRBF2 regulates macroautophagy as a component of Vps34 Complex I Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex Leucine and mTORC1: a complex relationship Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34 Differential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagy Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy Bif-1/endophilin B1: a candidate for crescent driving force in autophagy.The late endosome is essential for mTORC1 signaling Role of inositol trisphosphate receptors in autophagy in DT40 cells.Negative regulation of Vps34 by Cdk mediated phosphorylation.RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy.Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner.Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).Regulation of protein synthesis by amino acids in muscle of neonates.Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.Posttranslational modification of autophagy-related proteins in macroautophagy Mitochondrial Ca(2+) signals in autophagy.BECLIN 1-VPS34 COMPLEX ARCHITECTURE: UNDERSTANDING THE NUTS AND BOLTS OF THERAPEUTIC TARGETS.mTor signaling in skeletal muscle during sepsis and inflammation: where does it all go wrong?Leucyl-tRNA Synthetase Activates Vps34 in Amino Acid-Sensing mTORC1 Signaling.Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.Regulation of mTORC1 by lysosomal calcium and calmodulin.Autophagy regulation by nutrient signaling.Autophagy: regulation and role in disease.Leucine alleviates dexamethasone-induced suppression of muscle protein synthesis via synergy involvement of mTOR and AMPK pathways.Mechanisms of amino acid sensing in mTOR signaling pathway.When autophagy meets viruses: a double-edged sword with functions in defense and offense.Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle How phosphoinositide 3-phosphate controls growth downstream of amino acids and autophagy downstream of amino acid withdrawal.Targeting the PI3K pathway for cancer therapy.Control of cell growth: Rag GTPases in activation of TORC1.An overview of autophagy: morphology, mechanism, and regulation.AKT-independent PI3-K signaling in cancer - emerging role for SGK3.Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.Vps34 and PLD1 take center stage in nutrient signaling: their dual roles in regulating autophagy.Orexin/hypocretin activates mTOR complex 1 (mTORC1) via an Erk/Akt-independent and calcium-stimulated lysosome v-ATPase pathway.Withdrawal of essential amino acids increases autophagy by a pathway involving Ca2+/calmodulin-dependent kinase kinase-β (CaMKK-β)

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P2860

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells

http://www.wikidata.org/entity/Q24643834

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@ast

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@en

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@nl

type

label

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@ast

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@en

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@nl

prefLabel

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@ast

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@en

hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@nl

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P2860

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Biochemical Journal

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hVps15, but not Ca2+/CaM, is r ...... n of hVps34 in mammalian cells

@en

P2093

Haiyan Wu

http://www.w3.org/2001/XMLSchema#string

Jonathan M Backer

http://www.w3.org/2001/XMLSchema#string

Rachel S Schnur

http://www.w3.org/2001/XMLSchema#string

Rory J Flinn

http://www.w3.org/2001/XMLSchema#string

Ying Yan

http://www.w3.org/2001/XMLSchema#string

P2860

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

Human VPS34 and p150 are Rab7 interacting partners

Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting.

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747-55

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scholarly article

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2777406

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10.1042/BJ20081865

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P433

3

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P478

417

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2009-02-01T00:00:00Z

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P5875

23424738

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P698

18957027

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P932

2652830

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