Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
about
Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase.MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesisCrystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement RevisitedAn ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF.A MurF inhibitor that disrupts cell wall biosynthesis in Escherichia coli.Purification, crystallization and preliminary X-ray crystallographic analysis of the UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (MurF) from Acinetobacter baumannii.Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.Crystallization and preliminary X-ray analysis of a UDP-MurNAc-tripeptide D-alanyl-D-alanine-adding enzyme (PaMurF) from Pseudomonas aeruginosa.Cytoplasmic steps of peptidoglycan biosynthesis.Potential Antibacterial Targets in Bacterial Central Metabolism.The Gewald multicomponent reaction.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Biochemical characterisation of the chlamydial MurF ligase, and possible sequence of the chlamydial peptidoglycan pentapeptide stem.The biology of Mur ligases as an antibacterial target.Insight into the structural requirements of thiophene-3-carbonitriles-based MurF inhibitors by 3D-QSAR, molecular docking and molecular dynamics study.Effect of 4-methoxy 1-methyl 2-oxopyridine 3-carbamide on Staphylococcus aureus by inhibiting UDP-MurNAc-pentapeptide, peptidyl deformylase and uridine monophosphate kinase.MurF inhibitors with antibacterial activity: effect on muropeptide levels.A single amino acid substitution in the MurF UDP-MurNAc-pentapeptide synthetase renders Streptococcus pneumoniae dependent on CO2 and temperature.BoBER: web interface to the base of bioisosterically exchangeable replacements.
P2860
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P2860
Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structure of MurF from Strepto ...... r exhibits interdomain closure
@ast
Structure of MurF from Strepto ...... r exhibits interdomain closure
@en
Structure of MurF from Strepto ...... r exhibits interdomain closure
@nl
type
label
Structure of MurF from Strepto ...... r exhibits interdomain closure
@ast
Structure of MurF from Strepto ...... r exhibits interdomain closure
@en
Structure of MurF from Strepto ...... r exhibits interdomain closure
@nl
prefLabel
Structure of MurF from Strepto ...... r exhibits interdomain closure
@ast
Structure of MurF from Strepto ...... r exhibits interdomain closure
@en
Structure of MurF from Strepto ...... r exhibits interdomain closure
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure of MurF from Strepto ...... r exhibits interdomain closure
@en
P2093
Bruce A Beutel
Clarissa G Jakob
Claude G Lerner
Diane M Bartley
Elizabeth H Fry
Geoffrey F Stamper
John E Harlan
Karl A Walter
Kenton L Longenecker
Larry R Solomon
P2860
P304
P3181
P356
10.1110/PS.051604805
P407
P577
2005-12-01T00:00:00Z