Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels
about
The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal sizeAdeno-associated virus-mediated microRNA delivery and therapeuticsAdeno-associated virus type 2 rep protein inhibits human papillomavirus type 16 E2 recruitment of the transcriptional coactivator p300.Human adeno-associated virus type 5 is only distantly related to other known primate helper-dependent parvoviruses.Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitroAAV's anatomy: roadmap for optimizing vectors for translational successRescue and autonomous replication of adeno-associated virus type 2 genomes containing Rep-binding site mutations in the viral p5 promoter.A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay.Productive replication of adeno-associated virus can occur in human papillomavirus type 16 (HPV-16) episome-containing keratinocytes and is augmented by the HPV-16 E2 protein.Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteinsAmino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro.High mobility group chromosomal protein 1 binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression.Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 proteinAdeno-associated virus: a key to the human genome?A maltose-binding protein/adeno-associated virus Rep68 fusion protein has DNA-RNA helicase and ATPase activitiesSequence requirements for binding of Rep68 to the adeno-associated virus terminal repeatsThe adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection.The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter.Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products.The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation.The Rep78 gene product of adeno-associated virus (AAV) self-associates to form a hexameric complex in the presence of AAV ori sequences.Mutational analysis of the adeno-associated virus type 2 Rep68 protein helicase motifs.Sequence requirements for stable binding and function of Rep68 on the adeno-associated virus type 2 inverted terminal repeats.Birth of a new therapeutic platform: 47 years of adeno-associated virus biology from virus discovery to licensed gene therapy.Transcriptional analysis of the adeno-associated virus integration site.Identification of an adeno-associated virus Rep protein binding site in the adenovirus E2a promoter.Cardiac gene therapy: from concept to reality.Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter.Charged-to-alanine scanning mutagenesis of the N-terminal half of adeno-associated virus type 2 Rep78 protein.Comparative characterization of rep proteins from the helper-dependent adeno-associated virus type 2 and the autonomous goose parvovirus.Adeno-associated virus Rep78 protein interacts with protein kinase A and its homolog PRKX and inhibits CREB-dependent transcriptional activationSite-specific integration of an adeno-associated virus vector plasmid mediated by regulated expression of rep based on Cre-loxP recombination.Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexesCharge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants.Studies of the mechanism of transactivation of the adeno-associated virus p19 promoter by Rep protein.Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promotersSubcellular compartmentalization of adeno-associated virus type 2 assembly.Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins.Control of adeno-associated virus type 2 cap gene expression: relative influence of helper virus, terminal repeats, and Rep proteins.
P2860
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P2860
Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@ast
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@en
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@nl
type
label
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@ast
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@en
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@nl
prefLabel
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@ast
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@en
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@nl
P2093
P2860
P1433
P1476
Analysis of adeno-associated v ...... ate AAV p5 and p19 mRNA levels
@en
P2093
Chejanovsky N
Kyöstiö SR
Weitzman MD
P2860
P304
P407
P577
1994-05-01T00:00:00Z