Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
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Neuropilins: expression and roles in the epitheliumNeuropilins and liverNovel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinomaNeuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality.Protein kinase LKB1 promotes RAB7-mediated neuropilin-1 degradation to inhibit angiogenesis.Production of soluble human vascular endothelial growth factor VEGF-A165-heparin binding domain in Escherichia coli.Targeted intracellular delivery of proteins with spatial and temporal control.Quantitative ratiometric discrimination between noncancerous and cancerous prostate cells based on neuropilin-1 overexpression.Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma.MiR-148a, a microRNA upregulated in the WNT subgroup tumors, inhibits invasion and tumorigenic potential of medulloblastoma cells by targeting Neuropilin 1.Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3Expression of semaphorin 3A and neuropilin 1 with clinicopathological features and survival in human tongue cancer.Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors.Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by Neuropilin 1Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers.Nordihydroguaiaretic acid impairs prostate cancer cell migration and tumor metastasis by suppressing neuropilin 1.How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns.Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity.The emerging role of class-3 semaphorins and their neuropilin receptors in oncology.Neuropilin-1 as Therapeutic Target for Malignant Melanoma.The origin of prostate metastases: emerging insights.VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors.Vascular Endothelial Growth Factor A Regulates the Secretion of Different Angiogenic Factors in Lung Cancer Cells.Pleiotrophin exerts its migration and invasion effect through the neuropilin-1 pathwayLebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis.Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway.Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation.VEGF as a potential target in lung cancer.Co-targeting of EGF receptor and neuropilin-1 overcomes cetuximab resistance in pancreatic ductal adenocarcinoma with integrin β1-driven Src-Akt bypass signaling.Architecture and Hydration of the Arginine Binding Site of Neuropilin-1.Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells.N-terminal modification of VEGF-A C terminus-derived peptides delineates structural features involved in neuropilin-1 binding and functional activity.Neuropilin-1 promotes the oncogenic Tenascin-C/integrin β3 pathway and modulates chemoresistance in breast cancer cells.
P2860
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P2860
Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@ast
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@en
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@nl
type
label
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@ast
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@en
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@nl
prefLabel
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@ast
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@en
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@nl
P2093
P2860
P356
P1476
Neuropilin-1 antagonism in hum ...... and enhances chemosensitivity
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6605539
P407
P577
2010-02-02T00:00:00Z
P5875
P6179
1004072206