Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle
about
Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domainThree-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamerTransmural expression of transient outward potassium current subunits in normal and failing canine and human heartsIon Channels in the HeartIon channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathEffective association of Kv channel-interacting proteins with Kv4 channel is mediated with their unique core peptidePalmitoylation of KChIP splicing variants is required for efficient cell surface expression of Kv4.3 channelsTuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcriptionC-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2Inhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.Spatial distributions of Kv4 channels and KChip2 isoforms in the murine heart based on laser capture microdissection.Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricleMolecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationAutocrine A2 in the T-system of ventricular myocytes creates transmural gradients in ion transport: a mechanism to match contraction with load?Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial FibrillationElectrophysiological remodeling in heart failureDeterminants of CREB degradation and KChIP2 gene transcription in cardiac memory.Roles of KChIP1 in the regulation of GABA-mediated transmission and behavioral anxiety.The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.Molecular basis for the transmural distribution of the transient outward current.Transmural gradients in Na/K pump activity and [Na+]I in canine ventricleMicrotubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacingMixed signals in heart failure: cancer rules.Cellular mechanism of premature ventricular contraction-induced cardiomyopathy.Regulation of cardiac excitation-contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to)).A-type potassium currents in smooth muscle.When the DREAM is gone: from basic science to future prospectives in pain management and beyond.Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytesThe long QT interval is not only inherited but is also linked to cardiac hypertrophy.Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.Unique cardiac Purkinje fiber transient outward current β-subunit composition: a potential molecular link to idiopathic ventricular fibrillation.Evolution of CpG island promoter function underlies changes in KChIP2 potassium channel subunit gene expression in mammalian heart.Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure.Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.Ion channels as novel therapeutic targets in heart failure.Impact of ancillary subunits on ventricular repolarization.
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P2860
Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulation of KChIP2 potassium ...... in canine and human ventricle
@ast
Regulation of KChIP2 potassium ...... in canine and human ventricle
@en
Regulation of KChIP2 potassium ...... in canine and human ventricle
@nl
type
label
Regulation of KChIP2 potassium ...... in canine and human ventricle
@ast
Regulation of KChIP2 potassium ...... in canine and human ventricle
@en
Regulation of KChIP2 potassium ...... in canine and human ventricle
@nl
prefLabel
Regulation of KChIP2 potassium ...... in canine and human ventricle
@ast
Regulation of KChIP2 potassium ...... in canine and human ventricle
@en
Regulation of KChIP2 potassium ...... in canine and human ventricle
@nl
P2093
P2860
P1476
Regulation of KChIP2 potassium ...... in canine and human ventricle
@en
P2093
D McKinnon
P2860
P304
P356
10.1111/J.1469-7793.2001.0119B.X
P407
P577
2001-05-15T00:00:00Z