Life and death of sensory hair cells expressing constitutively active TRPML3 - Wikidata - wikimedia - TriplyDB

Life and death of sensory hair cells expressing constitutively active TRPML3

Life and death of sensory hair cells expressing constitutively active TRPML3

http://www.wikidata.org/entity/Q24647910

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Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules Transplantation and survival of mouse inner ear progenitor/stem cells in the organ of Corti after cochleostomy of hearing-impaired guinea pigs: preliminary results.A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.Two ENU-induced alleles of Atp2b2 cause deafness in mice.Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice Small molecule activators of TRPML3 Constitutive activity of the human TRPML2 channel induces cell degeneration Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy Constitutive activity of TRP channels methods for measuring the activity and its outcome.Phosphoinositide isoforms determine compartment-specific ion channel activity A helix-breaking mutation in the epithelial Ca(2+) channel TRPV5 leads to reduced Ca(2+)-dependent inactivation.

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P2860

Life and death of sensory hair cells expressing constitutively active TRPML3

http://www.wikidata.org/entity/Q24647910

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մարտին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

name

Life and death of sensory hair cells expressing constitutively active TRPML3

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Life and death of sensory hair cells expressing constitutively active TRPML3

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Life and death of sensory hair cells expressing constitutively active TRPML3

@nl

type

label

Life and death of sensory hair cells expressing constitutively active TRPML3

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Life and death of sensory hair cells expressing constitutively active TRPML3

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Life and death of sensory hair cells expressing constitutively active TRPML3

@nl

prefLabel

Life and death of sensory hair cells expressing constitutively active TRPML3

@ast

Life and death of sensory hair cells expressing constitutively active TRPML3

@en

Life and death of sensory hair cells expressing constitutively active TRPML3

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P1433

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P1433

Journal of Biological Chemistry

P1476

Life and death of sensory hair cells expressing constitutively active TRPML3

@en

P2093

Christian Grimm

http://www.w3.org/2001/XMLSchema#string

Simone Jörs

http://www.w3.org/2001/XMLSchema#string

Stefan Heller

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.

A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype

The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration

Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice

Haplo-insufficiency revealed in deafwaddler mice when tested for hearing loss and ataxia

Genetic analyses of the mouse deafness mutations varitint-waddler (Va) and jerker (Espnje)

Acoustic overstimulation increases outer hair cell Ca2+ concentrations and causes dynamic contractions of the hearing organ.

Plasma membrane Ca2+-ATPase isoform 2a is the PMCA of hair bundles.

Parvalbumin 3 is an abundant Ca2+ buffer in hair cells.

Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype.

P304

13823-13831

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scholarly article

P356

10.1074/JBC.M809045200

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P407

P433

20

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284

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2009-03-19T00:00:00Z

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19299509

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P932

2679483

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