Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI - Wikidata - wikimedia - TriplyDB

Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI

Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI

http://www.wikidata.org/entity/Q24649961

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Mutations in the SLC2A9 gene cause hyperuricosuria and hyperuricemia in the dog Sex and age interaction with genetic association of atherogenic uric acid concentrations Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series The genetics of hyperuricaemia and gout Predictive value of 8 genetic loci for serum uric acid concentration Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach Association between SLC2A9 (GLUT9) gene polymorphisms and gout susceptibility: an updated meta-analysis.Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians A genome-wide association study of serum uric acid in African Americans.Uric acid transport and disease Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates Polymorphisms in the presumptive promoter region of the SLC2A9 gene are associated with gout in a Chinese male population.Genome-wide scan identifies a quantitative trait locus at 4p15.3 for serum urate Serum uric acid levels are associated with polymorphisms in the SLC2A9, SF1, and GCKR genes in a Chinese population Changes in uric acid levels following bariatric surgery are not associated with SLC2A9 variants in the Swedish Obese Subjects Study Gout: a review of nonmodifiable and modifiable risk factors.Associations of serum uric acid and SLC2A9 variant with depressive and anxiety disorders: a population-based study.A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population Sex differences in renal and metabolic responses to a high-fructose diet in mice.Modulation of genetic associations with serum urate levels by body-mass-index in humans Serum uric acid concentrations and SLC2A9 genetic variation in Hispanic children: the Viva La Familia Study Relationship between Hyperuricemia and Haar-Like Features on Tongue Images.Early Life Exposure to Fructose Alters Maternal, Fetal and Neonatal Hepatic Gene Expression and Leads to Sex-Dependent Changes in Lipid Metabolism in Rat Offspring Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses Genomics and metabolomics of muscular mass in a community-based sample of UK females.Genome wide association study of uric acid in Indian population and interaction of identified variants with Type 2 diabetes Genotype-based changes in serum uric acid affect blood pressure.Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts.A common variant in the adiponutrin gene influences liver enzyme values.A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.SLC2A9--a fructose transporter identified as a novel uric acid transporter.Gout. Novel therapies for treatment of gout and hyperuricemia.Crystal ball gazing: new therapeutic targets for hyperuricaemia and gout.Facilitative glucose transporter 9, a unique hexose and urate transporter.Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans Genetic influence on variation in serum uric acid in American Indians: the strong heart family study.Effects of multiple genetic loci on the pathogenesis from serum urate to gout.Genetics of hyperuricemia and gout: implications for the present and future.Genetic risk scores, sex and dietary factors interact to alter serum uric acid trajectory among African-American urban adults.

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P2860

Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI

http://www.wikidata.org/entity/Q24649961

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2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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Barbara Kollerits

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Iris M Heid

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P2860

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

NFAT: ubiquitous regulator of cell differentiation and adaptation

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)

Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.

Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.

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10.2337/DC08-0349

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Florian Kronenberg

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