Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses
about
A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and plateletsProtein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activationRhoA downstream of G(q) and G(12/13) pathways regulates protease-activated receptor-mediated dense granule release in platelets.Inherited platelet-based bleeding disorders.Targeting protease-activated receptor-1 with cell-penetrating pepducins in lung cancer.Biological properties of a specific Galpha q/11 inhibitor, YM-254890, on platelet functions and thrombus formation under high-shear stressSignaling events underlying thrombus formation.Inherited defects in platelet signaling mechanisms.Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation.Congenital platelet disorders: overview of their mechanisms, diagnostic evaluation and treatment.GSK3beta is a negative regulator of platelet function and thrombosis.Protease-activated receptor (PAR) 1 and PAR4 differentially regulate factor V expression from human platelets.Impaired activation of platelets lacking protein kinase C-theta isoformProtease-activated receptor 4: from structure to function and back again.Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis.Activation of Rap1B by G(i) family members in platelets.Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets.Mutational analysis of the GNAS1 exons encoding the stimulatory G protein in five patients with pseudohypoparathyroidism type 1a.Phorbol 12-myristate 13-acetate (PMA) responsive sequence in Galphaq promoter during megakaryocytic differentiation. Regulation by EGR-1 and MAP kinase pathway.
P2860
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P2860
Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Platelet signal transduction d ...... th abnormal platelet responses
@ast
Platelet signal transduction d ...... th abnormal platelet responses
@en
Platelet signal transduction d ...... th abnormal platelet responses
@nl
type
label
Platelet signal transduction d ...... th abnormal platelet responses
@ast
Platelet signal transduction d ...... th abnormal platelet responses
@en
Platelet signal transduction d ...... th abnormal platelet responses
@nl
prefLabel
Platelet signal transduction d ...... th abnormal platelet responses
@ast
Platelet signal transduction d ...... th abnormal platelet responses
@en
Platelet signal transduction d ...... th abnormal platelet responses
@nl
P2093
P2860
P921
P356
P1476
Platelet signal transduction d ...... th abnormal platelet responses
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.16.8750
P407
P577
1997-08-05T00:00:00Z