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Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

http://www.wikidata.org/entity/Q24651175

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Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis.Carboxy-terminus of CXCR7 regulates receptor localization and function Ubiquitination of CXCR7 controls receptor trafficking β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6 International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2 CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression Atypical Chemokine Receptors and Their Roles in the Resolution of the Inflammatory Response Allosteric Modulation of Chemoattractant Receptors Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axis Collective cell migration in development The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases MIF and CXCL12 in Cardiovascular Diseases: Functional Differences and Similarities Biased and g protein-independent signaling of chemokine receptors CXCL12 chemokine and GABA neurotransmitter systems crosstalk and their putative roles CXCL12 chemokine and its receptors as major players in the interactions between immune and nervous systems Endocytic trafficking of chemokine receptors Chemokines as effector and target molecules in vascular biology The physiological relevance of functional selectivity in dopamine signalling Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis--Lessons From Pharmacological and Genetic Models CXCR7 protein expression in human adult brain and differentiated neurons Disruption of neuronal CXCR4 function by opioids: preliminary evidence of ferritin heavy chain as a potential etiological agent in neuroAIDS CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway.Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.GPR54 regulates ERK1/2 activity and hypothalamic gene expression in a Gα(q/11) and β-arrestin-dependent manner.CXCR7 controls competition for recruitment of β-arrestin 2 in cells expressing both CXCR4 and CXCR7.CXCR7 expression disrupts endothelial cell homeostasis and causes ligand-dependent invasion.The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.Emerging concepts and approaches for chemokine-receptor drug discovery.Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinoma C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment.Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells.Chaperoning G protein-coupled receptors: from cell biology to therapeutics Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling.Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.A Comprehensive Analysis of CXCL12 Isoforms in Breast Cancer(1,2.)Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma

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Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

http://www.wikidata.org/entity/Q24651175

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@ast

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@en

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@nl

type

label

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@ast

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@en

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@nl

prefLabel

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@ast

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@en

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@nl

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PNAS.0912852107

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Proceedings of the National Academy of Sciences of the United States of America

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Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

@en

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Christopher M Lam

http://www.w3.org/2001/XMLSchema#string

Craig Gerard

http://www.w3.org/2001/XMLSchema#string

Jihee Kim

http://www.w3.org/2001/XMLSchema#string

Norma P Gerard

http://www.w3.org/2001/XMLSchema#string

Robert J Lefkowitz

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Seungkirl Ahn

http://www.w3.org/2001/XMLSchema#string

Stewart Craig

http://www.w3.org/2001/XMLSchema#string

Sudarshan Rajagopal

http://www.w3.org/2001/XMLSchema#string

P2860

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

AMD3100 is a CXCR7 ligand with allosteric agonist properties

Transduction of receptor signals by beta-arrestins

The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

Control of chemokine-guided cell migration by ligand sequestration

C5L2, a nonsignaling C5A binding protein

Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor

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628-32

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890104

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10.1073/PNAS.0912852107

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2

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107

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2010-01-12T00:00:00Z

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40696015

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20018651

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2818968

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