Through the looking glass, mechanistic insights from enantiomeric human defensins
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Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 functionSometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptideInvariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1Trp-26 imparts functional versatility to human alpha-defensin HNP1Peptides and Peptidomimetics for Antimicrobial Drug DesignResonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMRNMR Solution Structure and Condition-Dependent Oligomerization of the Antimicrobial Peptide Human Defensin 5Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37Initial Insights into Structure-Activity Relationships of Avian DefensinsFunctional Determinants of Human Enteric -Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACEHuman -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide NanonetsTurning defense into offense: defensin mimetics as novel antibiotics targeting lipid IIHuman defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against Staphylococcus aureusBeta-Defensin 124 Is Required for Efficient Innate Immune Responses in Prostate Epithelial RWPE-1 Cells.Molecular evolution of the primate α-/θ-defensin multigene family.Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralizationMolecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogensNature versus design: the conformational propensities of D-amino acids and the importance of side chain chirality.Sub-inhibitory concentrations of human α-defensin potentiate neutralizing antibodies against HIV-1 gp41 pre-hairpin intermediates in the presence of serum.pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37Antimicrobial peptides and gut microbiota in homeostasis and pathology.Effect of selectively introducing arginine and D-amino acids on the antimicrobial activity and salt sensitivity in analogs of human beta-defensins.Human defensins 5 and 6 enhance HIV-1 infectivity through promoting HIV attachment.Contribution of microbiota to the intestinal physicochemical barrier.Mirror image proteins.Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II.Multifaceted mechanisms of HIV-1 entry inhibition by human α-defensinNatural antimicrobial peptides as promising anti-HIV candidates.Loss of Innate Host Defense Following Unprotected Vaginal SexDefensin DEFB103 bidirectionally regulates chemokine and cytokine responses to a pro-inflammatory stimulus.Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization Ability of Human Enteric Defensin 5Functional consequences of retro-inverso isomerization of a miniature protein inhibitor of the p53-MDM2 interaction.Database-Guided Discovery of Potent Peptides to Combat HIV-1 or SuperbugsDefensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut.α-Defensins in human innate immunity.Antimicrobial peptides: agents of border protection for companion animals.Activity of Genital Tract Secretions and Synthetic Antimicrobial Peptides against Group B Streptococcus.Targeting and inactivation of bacterial toxins by human defensins.Structure-Based Design of Hepatitis C Virus Vaccines that Elicit Neutralizing Antibody Responses to a Conserved Epitope.Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5.
P2860
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P2860
Through the looking glass, mechanistic insights from enantiomeric human defensins
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Through the looking glass, mechanistic insights from enantiomeric human defensins
@ast
Through the looking glass, mechanistic insights from enantiomeric human defensins
@en
Through the looking glass, mechanistic insights from enantiomeric human defensins
@nl
type
label
Through the looking glass, mechanistic insights from enantiomeric human defensins
@ast
Through the looking glass, mechanistic insights from enantiomeric human defensins
@en
Through the looking glass, mechanistic insights from enantiomeric human defensins
@nl
altLabel
Through the Looking Glass, Mechanistic Insights from Enantiomeric Human Defensins
@en
prefLabel
Through the looking glass, mechanistic insights from enantiomeric human defensins
@ast
Through the looking glass, mechanistic insights from enantiomeric human defensins
@en
Through the looking glass, mechanistic insights from enantiomeric human defensins
@nl
P2093
P2860
P356
P1476
Through the looking glass, mechanistic insights from enantiomeric human defensins
@en
P2093
Erik de Leeuw
Guozhang Zou
Jianfeng Wang
Marzena Pazgier
Robert I Lehrer
Wei-Yue Lu
Weirong Yuan
P2860
P304
29180-29192
P356
10.1074/JBC.M109.018085
P407
P577
2009-07-29T00:00:00Z