R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance - Wikidata - wikimedia - TriplyDB

R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance

R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance

http://www.wikidata.org/entity/Q24653939

about

Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use Current updates on oxazolidinone and its significance Revisiting the structures of several antibiotics bound to the bacterial ribosome The Antibiotic Thermorubin Inhibits Protein Synthesis by Binding to Inter-Subunit Bridge B2a of the Ribosome Targeting Antibiotic Resistance Repurposing Clinical Molecule Ebselen to Combat Drug Resistant Pathogens Antibiotics in the clinical pipeline at the end of 2015.Minocycline modulates NFκB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells.Probing translation with small-molecule inhibitors Cellular pharmacodynamics of the novel biaryloxazolidinone radezolid: studies with infected phagocytic and nonphagocytic cells, using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila Pipeline of Known Chemical Classes of Antibiotics.Structural basis for cross-resistance to ribosomal PTC antibiotics.Advances in MRSA drug discovery: where are we and where do we need to be?Antimicrobial resistance in Bacteroides spp.: occurrence and dissemination.Antibacterial oxazolidinones: emerging structure-toxicity relationships.Linezolid, the first oxazolidinone antibacterial agent.On the specificity of antibiotics targeting the large ribosomal subunit.The oxazolidinones: past, present, and future.Antibiotics in development targeting protein synthesis.The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance.Prospects for new antibiotics: a molecule-centered perspective.New antibacterial agents: patent applications published in 2010.Novel Oxazolidinone Antibacterial Analogues with a Substituted Ligustrazine C-ring Unit.Recent Advances in the Rational Design and Optimization of Antibacterial Agents.Linezolid Resistance in Staphylococci.Cellular pharmacokinetics of the novel biaryloxazolidinone radezolid in phagocytic cells: studies with macrophages and polymorphonuclear neutrophils.Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded hydrogels.An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants.Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations.Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700).Elevated linezolid resistance in clinical cfr-positive Staphylococcus aureus isolates is associated with co-occurring mutations in ribosomal protein L3.Complex long-distance effects of mutations that confer linezolid resistance in the large ribosomal subunit.2,4-Diamino-6,7-dimethylpteridine as a fluorescent ligand for binding and sensing an orphan cytosine in RNA duplexes.

P2860

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P2860

R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance

http://www.wikidata.org/entity/Q24653939

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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Antimicrobial Agents and Chemotherapy

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R chi-01, a new family of oxaz ...... ome-based linezolid resistance

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P2093

Erin M Duffy

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Eugene Skripkin

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Joseph A Ippolito

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Joseph DeVito

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Joyce Sutcliffe

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Laura Lawrence

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Timothy S McConnell

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P2860

The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria

In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens

Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721

The structural basis of ribosome activity in peptide bond synthesis

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression

Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

VMD: visual molecular dynamics

Raster3D: photorealistic molecular graphics

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10.1128/AAC.01193-07

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10

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52

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François Franceschi

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23133629

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