A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid
about
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid productionA novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cellsLysophospholipids and their receptors in the central nervous systemLysophospholipid receptors LPA1–3 are not required for the inhibitory effects of LPA on mouse retinal growth conesDifferential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5Immunohistological localization of the myelinating cell-specific receptor LP(A1)Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtypeEdg-2 in myelin-forming cells: isoforms, genomic mapping, and exclusion in Charcot-Marie-Tooth diseaseLPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activationInternational Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsBiological roles of lysophospholipid receptors revealed by genetic null mice: an update.Rho/ROCK pathway is essential to the expansion, differentiation, and morphological rearrangements of human neural stem/progenitor cells induced by lysophosphatidic acidLysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity.Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters.Lysophosphatidic acid (LPA) signaling in vertebrate reproduction.Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance.LPA receptor signaling: pharmacology, physiology, and pathophysiology.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesionsDual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rhoAggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice.Metabolic engineering of plant cells in a space environment.Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis.Neurobiology of lysophosphatidic acid signaling.Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling.Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Anatomical location of LPA1 activation and LPA phospholipid precursors in rodent and human brain.Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1Lysophospholipid receptors are differentially expressed in rat terminal Schwann cells, as revealed by a single cell rt-PCR and in situ hybridization.Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA).Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acidThe lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival.Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity.Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiationInhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling.
P2860
Q24297673-00A63728-814C-41CD-8FC6-9614F7971922Q24658261-AA7994C3-97CD-46CA-9111-A7BDF39B5EE2Q24673806-2AE4E1D4-2C61-4D87-8F64-264B7E235421Q24678857-B82167A3-D3ED-489C-AF35-3CC121950F3DQ26859168-0189D86E-7B33-4CF3-A409-DFCD31DFC0FFQ27337671-35F0975E-FA9C-4533-9B35-4419F6F7327CQ28138229-0BB9A4D5-AC2A-4A3C-B227-EE9E0CFFA2A1Q28214471-B2BA4C09-ECF7-48C5-936E-65BB913CDF98Q28297208-48415DDF-4CCE-46E3-9E8F-79D8D7F4D238Q28350001-623AD56D-68F9-41B7-8D9E-943D0A2CBF43Q28583631-E5BF9D8B-3EFD-4CAD-A935-EE6920E8C6E9Q28589775-5D904223-AEFD-4062-A63F-33E7360FAB3DQ30429523-CF1EB4B7-5366-4EEE-AE07-6B78A07E6FD9Q30486707-121EC91B-8AF7-42F8-889F-DCAFB984A79FQ30487082-45FA6EEC-F004-4E5F-9D4A-531E0FF57D86Q30538666-EE9B0AFD-8083-437B-88E1-CB324189F7ADQ30573574-3D9DA993-F271-4E99-9DB1-C3F54DEFC19DQ30708920-A2688396-C35A-4351-B873-917BD968CEAEQ33636488-ABC032B0-19C8-4B7D-8754-F95ADF5694F6Q33753311-70940B6C-43C8-40CE-B089-E8E31204B7BAQ33825153-FE586797-0A11-44C1-A22F-4399D6B8D7E8Q33840143-2135510A-E8BB-4B1E-A6C5-0337AFC6A500Q33864168-D05F6510-55CB-4EF1-AC37-788CF1E39017Q33902903-6B1525CD-96A8-4735-B7EA-7CC21C5DC82FQ34043311-49839FC3-CB21-4BFF-A81B-C4271721E9ACQ34187876-19CAC41B-29C7-4EDF-8999-18B7C7362FD0Q34285790-4B1576B7-AB25-4FD3-9FC7-E7D997A396B1Q34324614-9860FE42-C0A8-4A84-AD59-4CBC1A1009B4Q35017623-AA0815DF-8CF7-446A-A813-CB1E2EB1CF34Q35216929-39ECAA66-6497-4451-9EE3-665C96C98293Q35551835-ECD49492-F71C-4EC1-8A94-BEB2234B4B6BQ35598539-9A15869E-FD26-425C-A077-89FB0CD1BF96Q35668649-D6156A97-0AC0-42E6-8151-EE3A5C31765DQ35688245-360344B9-6887-4527-8297-7C0A4DA6004BQ36083085-F886F446-9ADC-4469-9AAB-C07C4488F258Q36341018-977B46DB-0EF3-45FA-8CE8-CA577CE40DCDQ36395318-A99745E0-F210-489D-87D6-915239F746DFQ36498359-74CB50AB-BCF1-4D0C-8C63-E6E2C708DF15Q36512021-CCA4A8F0-1252-4A19-BEB4-9B71BF3AB442Q36631057-4B5E84F4-D77D-4A18-B629-BC6B1ADFFBBA
P2860
A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A single receptor encoded by v ...... onses to lysophosphatidic acid
@ast
A single receptor encoded by v ...... onses to lysophosphatidic acid
@en
A single receptor encoded by v ...... onses to lysophosphatidic acid
@nl
type
label
A single receptor encoded by v ...... onses to lysophosphatidic acid
@ast
A single receptor encoded by v ...... onses to lysophosphatidic acid
@en
A single receptor encoded by v ...... onses to lysophosphatidic acid
@nl
prefLabel
A single receptor encoded by v ...... onses to lysophosphatidic acid
@ast
A single receptor encoded by v ...... onses to lysophosphatidic acid
@en
A single receptor encoded by v ...... onses to lysophosphatidic acid
@nl
P2093
P2860
P356
P1476
A single receptor encoded by v ...... onses to lysophosphatidic acid
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.11.6151
P407
P577
1998-05-26T00:00:00Z