The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity - Wikidata - wikimedia - TriplyDB

The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

http://www.wikidata.org/entity/Q24654198

about

Role of Bmi-1 in regulation of ionizing irradiation-induced epithelial-mesenchymal transition and migration of breast cancer cells p53 opens the mitochondrial permeability transition pore to trigger necrosis Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization.Epigenetics and therapeutic targets mediating neuroprotection Activation of Wnt/β-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of aging.Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro.Bmi1 regulates auditory hair cell survival by maintaining redox balance.Distinct and separable roles for EZH2 in neurogenic astroglia p38 MAPK-Mediated Bmi-1 down-regulation and defective proliferation in ATM-deficient neural stem cells can be restored by Akt activation.p53 and mitochondrial function in neurons.Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain microRNA-141 regulates BMI1 expression and induces senescence in human diploid fibroblasts.An evolving view of epigenetic complexity in the brain.Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer.Bmi-1 absence causes premature brain degeneration Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression.Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98.Enhancing chemotherapy response with Bmi-1 silencing in ovarian cancer An anticlastogenic function for the Polycomb Group gene Bmi1.βTrCP regulates BMI1 protein turnover via ubiquitination and degradation.Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance.p53, oxidative stress, and aging Epigenetic mechanisms of neuroplasticity and the implications for stroke recovery.Transcriptional repression of Sin3B by Bmi-1 prevents cellular senescence and is relieved by oncogene activation BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer.Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice Anti-aging Effect of Transplanted Amniotic Membrane Mesenchymal Stem Cells in a Premature Aging Model of Bmi-1 Deficiency.miR-300 mediates Bmi1 function and regulates differentiation in primitive cardiac progenitors.Bmi1 is required for regeneration of the exocrine pancreas in mice Bmi1 overexpression in the cerebellar granule cell lineage of mice affects cell proliferation and survival without initiating medulloblastoma formation.A positive feedback loop regulates the expression of polycomb group protein BMI1 via WNT signaling pathway.Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins.Epigenetic modulation of gene expression governs the brain's response to injury Chromatin-modifying agents for epigenetic reprogramming and endogenous neural stem cell-mediated repair in stroke.Epigenetic regulation in adult stem cells and cancers.A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells.Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance.Bmi1 plays an important role in dentin and mandible homeostasis by maintaining redox balance.Heterozygous knockout of the Bmi-1 gene causes an early onset of phenotypes associated with brain aging.

P2860

Q21089647-F454C424-0BA1-4B50-AC47-215167D5E76A Q24338796-30A72E0A-C85C-422E-BE62-26BFF1C57474 Q27304699-87034134-1810-46F9-950C-3193906C2319 Q28080633-42F9C1CF-7906-4422-846B-7B25C8A139FE Q30354724-38A5A681-451F-4999-AAC1-9AE0B0AB2CD3 Q30371668-B30468A9-5DD6-4605-AAD9-4D319A56723C Q30396588-444DF22F-F02D-4436-A871-2FA2F6D3324E Q33655867-007898B1-E947-42B4-81B8-93FE1A90A4F1 Q33816007-5B959B7E-4CD6-44F5-89E2-EE3B0587A42A Q33819250-878FDEE8-4ED4-40E5-B55D-12BFF8900372 Q33975692-76E62CC2-F4A2-4668-BFA6-F25455700B96 Q34038397-A5CED3B3-E443-4E32-B357-D6533B9836B0 Q34079396-727F4559-E509-4571-BED1-365F2A046EAE Q34134903-2339A8BA-CC96-404D-B6EF-A475A2C701CF Q34171573-F127FDD1-90D1-4234-A75D-31FE48102B25 Q34182026-8527BCCC-7A6A-4152-81CC-7780C6A4F829 Q34402813-13E34588-A445-44BF-91E2-34B9E1CBB0C2 Q34561758-CB0F5669-E293-4062-85C4-72FDC34A4D8C Q34704011-9488DAB6-DAC1-4059-9B08-1103D66C4351 Q34750024-A540536D-E472-4267-9D72-431D46517C01 Q35051176-BC385E1E-B447-4A69-BE30-9AC8A4874E45 Q35093071-A60C8348-B9BE-454A-87B7-9529F588FDC4 Q35151322-D4E59A7C-4DA1-40B9-9732-C6B42BF15F99 Q35220512-6D8BFFD4-8053-4EE1-90E1-4DEE749C5387 Q35226557-26B147A9-5F4D-4C26-8E29-680A709C970D Q35691501-72E4FA4B-3307-4075-91EF-BC8CB0C2EF32 Q35940978-0409A60C-5716-455E-B9D6-446573D374CD Q36061843-511FFB5E-4BB3-4044-AB7E-E818785CA390 Q36246408-C5D1E7D1-CF21-44C4-B9FA-DB83570C0079 Q36359854-20072585-5E26-496B-939B-7E0CBA9DFEAC Q36486005-2E00AFF2-4AB7-4994-8203-D0CC819288C4 Q36579560-3154E9AC-8D2D-458B-9A67-6F82F2D8C766 Q36616998-43B6AB3B-C527-4A0B-BF19-406E98D8F2AA Q36995424-26DEF48F-5F8F-46D5-87E9-BA5A2CB04AB5 Q37151715-DF9056AF-D50E-4D0D-AAAB-C9C75D4F66C5 Q37366481-EAE73B70-C4A7-474A-8004-3ABD2CC4F772 Q37392683-6EF94A72-94C0-4C8B-BAFF-FBF78C2088EC Q37426724-90915CF6-61DF-4BA5-AA3B-F102E591F66F Q37448119-BB25A8FF-E306-4B3B-B933-2B5E10359452 Q37471039-663190D5-9960-4598-8114-D1CD525CA462

P2860

The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

http://www.wikidata.org/entity/Q24654198

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@ast

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@en

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@nl

type

label

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@ast

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@en

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@nl

prefLabel

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@ast

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@en

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@nl

P1433

Q24654198-1D7070BC-62BF-44BD-A24E-4C396E97ED39

P1476

Q24654198-A45C0C87-6871-436E-BA27-FDF89ED0BF28

P2093

Q24654198-02656C35-D182-4908-99AE-5B518EF2A8F5

Q24654198-14A368B5-CAB0-4B82-A6F8-BBE555EF8F8B

Q24654198-55CF4723-281E-4ECC-BF33-882ED4257958

Q24654198-9E52A091-F450-40C8-8764-C474BD7FE475

Q24654198-B3650BE4-FEE3-41E7-B9EC-E3B9CE220954

Q24654198-CB772032-EC9D-4D1D-A81E-796F25C5BF9B

Q24654198-E6CE42BE-958D-4275-853B-67D9100B6715

P2860

Q24654198-012892B8-94AA-43DD-83A7-18159B285B5F

Q24654198-03A6CD42-797A-4964-ABC3-C85DF9F90D02

Q24654198-06686A22-FFEA-4779-9FBE-390CC2D88105

Q24654198-0CFBB546-817C-436A-AFB1-EAD4056B9305

Q24654198-0F7D714A-B984-40FA-A956-BDC3939FEB75

Q24654198-13475062-6EC0-4E03-BFAB-E500042DFDBC

Q24654198-134CB62E-6C9D-46FD-9D55-505D4991DDDF

Q24654198-2F428910-47D0-4F2B-8F82-85B3AA1C4A87

Q24654198-31CBC488-6C6D-4D83-9B5D-9A52A2CE4052

Q24654198-4C4EEAD2-F537-4A1D-86DD-D7B89C0BEDA5

P304

Q24654198-4E587469-532C-4977-AE7C-74D08510B2D3

P31

Q24654198-C53A401E-7A8E-4CBE-AD3A-501787E4C808

P3181

Q24654198-BF6A6C29-CDA7-4C0F-A6D5-39B353874B08

P356

Q24654198-45E6368B-276D-4688-8CD1-FEDC006827DF

P407

Q24654198-98DE112B-3591-4126-A47A-2DC26A2E69DE

P433

Q24654198-C1D52024-0A2C-4626-A188-95BE0C6A0170

P478

Q24654198-E391D605-2059-43A5-B949-EED525B2D155

P577

Q24654198-49A323AD-E25B-4FEA-8206-EAC52E450C07

P698

Q24654198-189A79D8-6884-44E1-BB86-1AEC41C814F9

P932

Q24654198-2653C81D-E5D5-4652-9B93-D108969D653A

P3181

P356

JNEUROSCI.5303-08.2009

P1433

Journal of Neuroscience

P1476

The polycomb group gene Bmi1 r ...... ssing p53 pro-oxidant activity

@en

P2093

Francis Rodier

http://www.w3.org/2001/XMLSchema#string

Gilbert Bernier

http://www.w3.org/2001/XMLSchema#string

Jocelyn David

http://www.w3.org/2001/XMLSchema#string

José Ferreira

http://www.w3.org/2001/XMLSchema#string

Marie-Pier Champagne

http://www.w3.org/2001/XMLSchema#string

Mohamed Abdouh

http://www.w3.org/2001/XMLSchema#string

Wassim Chatoo

http://www.w3.org/2001/XMLSchema#string

P2860

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Acetylation is indispensable for p53 activation

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

Aging: a theory based on free radical and radiation chemistry

The INK4a/ARF network in tumour suppression

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

Regeneration beyond the glial scar

Divorcing ARF and p53: an unsettled case

P304

529-42

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2938475

http://www.w3.org/2001/XMLSchema#string

P356

10.1523/JNEUROSCI.5303-08.2009

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

29

http://www.w3.org/2001/XMLSchema#string

P577

2009-01-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19144853

http://www.w3.org/2001/XMLSchema#string

P932

2744209

http://www.w3.org/2001/XMLSchema#string