Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis - Wikidata - wikimedia - TriplyDB

Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

http://www.wikidata.org/entity/Q24655172

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ZNF703 gene amplification at 8p12 specifies luminal B breast cancer ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics Patterns of Chromosomal Aberrations in Solid Tumors Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors Genetic variants associated with breast size also influence breast cancer risk FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer High quality genomic copy number data from archival formalin-fixed paraffin-embedded leiomyosarcoma: optimisation of universal linkage system labelling Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers The role of FADD in pancreatic cancer cell proliferation and drug resistance Identification of MYST3 as a novel epigenetic activator of ERα frequently amplified in breast cancer.Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer.Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients.Polarity gene alterations in pure invasive micropapillary carcinomas of the breast Breast cancer genomes--form and function ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors.CG0009, a novel glycogen synthase kinase 3 inhibitor, induces cell death through cyclin D1 depletion in breast cancer cells.miR-503 represses human cell proliferation and directly targets the oncogene DDHD2 by non-canonical target pairing.Cyclin alterations in diverse cancers: Outcome and co-amplification network.Who is in the driver's seat in 8p12 amplifications? ZNF703 in luminal B breast tumors.Elevated ZNF703 Protein Expression Is an Independent Unfavorable Prognostic Factor for Survival of the Patients with Head and Neck Squamous Cell Carcinoma Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor.Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer.FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma.High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer Correlative Analysis of Genetic Alterations and Everolimus Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Results From BOLERO-2.Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling Reviewing once more the c-myc and Ras collaboration: converging at the cyclin D1-CDK4 complex and challenging basic concepts of cancer biology.Fibroblast growth factors and their receptors in cancer.The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.Functional characterization of EMSY gene amplification in human cancers.Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in 8p11-p12-amplified breast carcinomas.Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers.An mRNA Gene Expression-Based Signature to Identify FGFR1-Amplified Estrogen Receptor-Positive Breast Tumors.Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is associated with ERα over-expression in breast cancer.High-resolution genomic analysis of the 11q13 amplicon in breast cancers identifies synergy with 8p12 amplification, involving the mTOR targets S6K2 and 4EBP1.

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Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

http://www.wikidata.org/entity/Q24655172

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2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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Co-amplified genes at 8p12 and ...... major pathways in oncogenesis

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J A Martinez-Climent

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma

Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer

Transforming properties of TC-1 in human breast cancer: interaction with FGFR2 and beta-catenin signaling pathways

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

Breast tumor copy number aberration phenotypes and genomic instability

Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers.

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