GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits
about
GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIPRGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11RGS1 is expressed in monocytes and acts as a GTPase-activating protein for G-protein-coupled chemoattractant receptorsCytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifsGTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domainRGS-GAIP, a GTPase-activating protein for Galphai heterotrimeric G proteins, is located on clathrin-coated vesiclesRGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of GzalphaR9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rodsGIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathwaysInteraction between RGS7 and polycystinClathrin-coated vesicles bearing GAIP possess GTPase-activating protein activity in vitroActivator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunitsPlasma membrane localization is required for RGS4 function in Saccharomyces cerevisiaePromotion of G alpha i3 subunit down-regulation by GIPN, a putative E3 ubiquitin ligase that interacts with RGS-GAIPExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersThe mammalian calcium-binding protein, nucleobindin (CALNUC), is a Golgi resident proteinMembrane-associated GAIP is a phosphoprotein and can be phosphorylated by clathrin-coated vesiclesRegulators of G-protein signaling in the heart and their potential as therapeutic targets.Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo.Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10)Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cellsPalmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteinsPalmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signallingPalmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residueG beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interactionThe interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassemblyMultiple phosphorylation sites in RGS16 differentially modulate its GAP activityInteraction of human retinal RGS with G-protein alpha-subunitsExpression of GTPase-deficient Gialpha2 results in translocation of cytoplasmic RGS4 to the plasma membraneRGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamilyIdentification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domainRegulators of G Protein SignalingStructural Basis for the Selectivity of the RGS Protein, GAIP, for G i Family Members: IDENTIFICATION OF A SINGLE AMINO ACID DETERMINANT FOR SELECTIVE INTERACTION OF G i SUBUNITS WITH GAIPThe evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.Native human autoantibodies targeting GIPC1 identify differential expression in malignant tumors of the breast and ovaryA human monoclonal autoantibody to breast cancer identifies the PDZ domain containing protein GIPC1 as a novel breast cancer-associated antigen.A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration.rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases.
P2860
Q22003946-ECBFFC55-9AEB-460B-8AF3-2CAB9F8FEB8CQ22008566-35964D4F-6594-40E6-8D5B-A2104AB2343CQ22010529-B8263274-27DC-4FF7-A745-498D9885505AQ22254020-C99AAA5B-078E-4DD5-B0BB-436291557445Q24311627-9921B98D-0AD9-43DC-9C6E-DD251814045EQ24313026-B8EA0EF3-B07B-4D41-92C9-0CE15AA022B5Q24316172-CB2AFCF8-9D7B-42BA-A56E-EFB218246DCDQ24533588-522CA9DF-CAC7-4E7D-8E35-1696045E55EBQ24569573-F1830D2D-6112-4DCD-B25E-7669158985EFQ24633321-3EAFCAF9-319F-4B99-ABEB-2F00DEC90422Q24653605-9F03360F-DCF0-431C-BE71-50EDE10D4146Q24653707-E1169619-D5B8-4BD2-B334-CCD5D1D820EBQ24672332-37930CCC-B8AB-47C9-AAF8-BF0FEE7D57FFQ24674857-6AE58C4C-CC18-41BD-9D46-73A0FC05D6BAQ24680028-E5BB373D-67D0-4E7F-8E78-2F92EF50792DQ24681398-E62155DD-1CD5-4CA6-A545-AFF79F4BB8D5Q24682684-A9699CF7-4D50-40E3-8328-82C1AAE75887Q24682851-FA01860B-2409-4169-B365-0F76D91C46FDQ27686777-F709364E-76CB-4D17-8CC3-33CA93E39FC5Q27939571-D83E9555-3E5E-471A-9618-75F6BB6429A6Q28115997-45D0885B-5A88-472C-BD71-E1FDFA583D4BQ28138966-940D199F-EB9F-4B33-BE1E-AC8B74543377Q28141136-24284AF8-3217-40AA-B174-7820CB6BEFBCQ28141464-5332113D-EC19-4D5B-9434-78635F313373Q28184243-0928340A-D268-460F-A064-5F38B317857AQ28184264-E4ABED22-A7CC-4534-A1AE-CE37209DFAABQ28188095-AF0E3E23-DF7A-4856-8974-C53E38DAE4FBQ28205557-52B3B9EC-7DBA-4B4C-B9B8-8AF7323A6116Q28214410-90CD02BA-949D-4353-BD5B-F89BFAE0D8FEQ28247210-ED5C2118-9434-410F-AF53-C688AABC59F5Q28276163-EF7B7DD0-FA4F-4141-B0C4-FBE95ED0A79EQ28283407-2137F23C-8AE6-478D-A567-6BC3C9E57640Q28295415-993C1FF3-A6B8-4E3F-B69E-CFCE1A1066E1Q29302980-B09BEDE7-22D1-4CE7-9CE3-88E2D6FE769FQ29397097-7AB4DE6B-DB78-49DA-96BF-0CECAF6F7BCFQ30397640-66523E4A-2045-40C8-8B66-ECBAC4FFEFD5Q33362591-C1300259-902D-4A4F-8237-20F2DC27B434Q33362597-E7649396-726B-4126-8339-31CE62762A7AQ33799957-63CEFA95-A992-4E5A-B67D-9914A7CCA3F5Q33869434-B28ED443-773C-4010-960F-C493A526703D
P2860
GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@ast
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@en
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@nl
type
label
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@ast
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@en
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@nl
prefLabel
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@ast
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@en
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@nl
P2093
P2860
P356
P1476
GAIP is membrane-anchored by p ...... nd) form of G alpha i subunits
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.26.15203
P407
P577
1996-12-24T00:00:00Z