Rotavirus protein NSP3 (NS34) is bound to the 3' end consensus sequence of viral mRNAs in infected cells
about
RoXaN, a novel cellular protein containing TPR, LD, and zinc finger motifs, forms a ternary complex with eukaryotic initiation factor 4G and rotavirus NSP3Efficient translation of rotavirus mRNA requires simultaneous interaction of NSP3 with the eukaryotic translation initiation factor eIF4G and the mRNA 3' endRotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F.The stem-loop binding protein is required for efficient translation of histone mRNA in vivo and in vitroMammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanismsFour nucleotides are the minimal requirement for RNA recognition by rotavirus non-structural protein NSP3Recovery and characterization of a replicase complex in rotavirus-infected cells by using a monoclonal antibody against NSP2Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus VirulenceStress Response and Translation Control in Rotavirus InfectionThe battle between rotavirus and its host for control of the interferon signaling pathwayRotavirus non-structural proteins: structure and functionA ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAsA four-nucleotide translation enhancer in the 3'-terminal consensus sequence of the nonpolyadenylated mRNAs of rotavirus.Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex.Nuclear localization of cytoplasmic poly(A)-binding protein upon rotavirus infection involves the interaction of NSP3 with eIF4G and RoXaN.cis-Acting signals that promote genome replication in rotavirus mRNA.The 3'-terminal consensus sequence of rotavirus mRNA is the minimal promoter of negative-strand RNA synthesisRotavirus VP1 alone specifically binds to the 3' end of viral mRNA, but the interaction is not sufficient to initiate minus-strand synthesis.Challenging the Roles of NSP3 and Untranslated Regions in Rotavirus mRNA Translation.Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesisRotavirus variant replicates efficiently although encoding an aberrant NSP3 that fails to induce nuclear localization of poly(A)-binding proteinProducts of the porcine group C rotavirus NSP3 gene bind specifically to double-stranded RNA and inhibit activation of the interferon-induced protein kinase PKR.Deletion mapping of the rotavirus metalloprotein NS53 (NSP1): the conserved cysteine-rich region is essential for virus-specific RNA binding.Template-dependent, in vitro replication of rotavirus RNA.Rotavirus prevents the expression of host responses by blocking the nucleocytoplasmic transport of polyadenylated mRNAs.Identification of the RNA-binding, dimerization, and eIF4GI-binding domains of rotavirus nonstructural protein NSP3.Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1.Nondefective rotavirus mutants with an NSP1 gene which has a deletion of 500 nucleotides, including a cysteine-rich zinc finger motif-encoding region (nucleotides 156 to 248), or which has a nonsense codon at nucleotides 153-155.In vivo and in vitro phosphorylation of rotavirus NSP5 correlates with its localization in viroplasms.Serine protein kinase activity associated with rotavirus phosphoprotein NSP5.Involvement of the interferon-regulated antiviral proteins PKR and RNase L in reovirus-induced shutoff of cellular translation.Genomic analysis of codon, sequence and structural conservation with selective biochemical-structure mapping reveals highly conserved and dynamic structures in rotavirus RNAs with potential cis-acting functions.
P2860
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P2860
Rotavirus protein NSP3 (NS34) is bound to the 3' end consensus sequence of viral mRNAs in infected cells
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@ast
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@en
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@nl
type
label
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@ast
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@en
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@nl
prefLabel
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@ast
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@en
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@nl
P2093
P2860
P3181
P1433
P1476
Rotavirus protein NSP3 (NS34) ...... viral mRNAs in infected cells
@en
P2093
P2860
P304
P3181
P407
P577
1993-06-01T00:00:00Z