Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling - Wikidata - wikimedia - TriplyDB

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

http://www.wikidata.org/entity/Q24657627

about

Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47 The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47 Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors Radiotherapy combination opportunities leveraging immunity for the next oncology practice Interplay between Cellular and Molecular Inflammatory Mediators in Lung Cancer The impact of the myeloid response to radiation therapy Activated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its management NO to cancer: The complex and multifaceted role of nitric oxide and the epigenetic nitric oxide donor, RRx-001 Endothelial perturbations and therapeutic strategies in normal tissue radiation damage CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest Registered report: the CD47-signal regulated protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors PAI-1-dependent endothelial cell death determines severity of radiation-induced intestinal injury Signaling and stress: The redox landscape in NOS2 biology Early biomarker for radiation-induced wounds: day one post-irradiation assessment using hemoglobin concentration measured from diffuse optical reflectance spectroscopy.A hypothesis on biological protection from space radiation through the use of new therapeutic gases as medical counter measures.Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model.Blockade of CD47 increases survival of mice exposed to lethal total body irradiation Engagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells.CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapy Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1.sFRP-1 binds via its netrin-related motif to the N-module of thrombospondin-1 and blocks thrombospondin-1 stimulation of MDA-MB-231 breast carcinoma cell adhesion and migration.Six degrees of separation: the oxygen effect in the development of radiosensitizers.Upregulation of leukemia inhibitory factor (LIF) during the early stage of optic nerve regeneration in zebrafish The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47.Therapeutic Targeting of CD47 to Modulate Tissue Responses to Ischemia and Radiation.The diverse and complex roles of radiation on cancer treatment: therapeutic target and genome maintenance.CD47 Receptor Globally Regulates Metabolic Pathways That Control Resistance to Ionizing Radiation The convergence of radiation and immunogenic cell death signaling pathways.Activation of parenchymal CD47 promotes renal ischemia-reperfusion injury.Original insights on thrombospondin-1-related antireceptor strategies in cancer.Identification of TAX2 peptide as a new unpredicted anti-cancer agent.E2F8 as a Novel Therapeutic Target for Lung Cancer CD47 deficiency confers cell and tissue radioprotection by activation of autophagy.CD47 signaling pathways controlling cellular differentiation and responses to stress.Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis.Radioresistance of glioma stem cells: intrinsic characteristic or property of the 'microenvironment-stem cell unit'?Therapies using anti-angiogenic peptide mimetics of thrombospondin-1.Programmed cell removal: a new obstacle in the road to developing cancer.Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review.

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P2860

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

http://www.wikidata.org/entity/Q24657627

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@ast

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@en

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@nl

type

label

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@ast

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@en

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@nl

prefLabel

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@ast

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@en

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@nl

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SCITRANSLMED.3000139

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Science Translational Medicine

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Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

@en

P2093

David A Wink

http://www.w3.org/2001/XMLSchema#string

David R Soto-Pantoja

http://www.w3.org/2001/XMLSchema#string

Hubert B Shih

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Jeff S Isenberg

http://www.w3.org/2001/XMLSchema#string

Justin B Maxhimer

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Lisa A Ridnour

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Maria Tsokos

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William G Degraff

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P2860

Apoptotic cell thrombospondin-1 and heparin-binding domain lead to dendritic-cell phagocytic and tolerizing states

Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake

Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells

Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1

Tumour-educated macrophages promote tumour progression and metastasis

The response of the microvascular system to radiation: a review.

Thrombospondin 1 and vasoactive agents indirectly alter tumor blood flow.

Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.

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3ra7

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scholarly article

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10.1126/SCITRANSLMED.3000139

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3

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David D Roberts

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2009-10-01T00:00:00Z

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41453410

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20161613

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2811586

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