Waiting for two mutations: with applications to regulatory sequence evolution and the limits of Darwinian evolution
about
Does positive selection drive transcription factor binding site turnover? A test with Drosophila cis-regulatory modulesWhat fraction of the human genome is functional?The rate of establishment of complex adaptationsThe Jackprot Simulation Couples Mutation Rate with Natural Selection to Illustrate How Protein Evolution Is Not Random.What does it take to evolve an enhancer? A simulation-based study of factors influencing the emergence of combinatorial regulationDissecting darwinismScaling expectations for the time to establishment of complex adaptationsThe potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.Integrating horizontal gene transfer and common descent to depict evolution and contrast it with "common design".The rate of fitness-valley crossing in sexual populations.Changes in selective effects over time facilitate turnover of enhancer sequences.Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic AstrocytomaThe waiting time problem in a model hominin population.Conditional Immune Escape during Chronic Simian Immunodeficiency Virus InfectionAn evolutionary explanation for the presence of cancer nonstem cells in neoplasms.Multidimensional adaptive evolution of a feed-forward network and the illusion of compensation.Simulations of enhancer evolution provide mechanistic insights into gene regulation.Ancestral resurrection of the Drosophila S2E enhancer reveals accessible evolutionary paths through compensatory change.Complex role of space in the crossing of fitness valleys by asexual populations.The rate at which asexual populations cross fitness valleys.Spatial Moran Models I. Stochastic Tunneling in the Neutral Case.Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations.Frequency-dependent fitness induces multistability in coevolutionary dynamics.Natural variation of the expression pattern of the segmentation gene even-skipped in melanogasterSpatial Moran models, II: cancer initiation in spatially structured tissueWaiting longer for two mutations.Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations.Reply to Michael Behe.Toward the Darwinian transition: Switching between distributed and speciated states in a simple model of early life.Crossing fitness canyons by a finite population.Escaping an evolutionary lobster trap: drug resistance and compensatory mutation in a fluctuating environment.Argumentation and fallacies in creationist writings against evolutionary theory
P2860
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P2860
Waiting for two mutations: with applications to regulatory sequence evolution and the limits of Darwinian evolution
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Waiting for two mutations: wit ...... limits of Darwinian evolution
@ast
Waiting for two mutations: wit ...... limits of Darwinian evolution
@en
Waiting for two mutations: wit ...... limits of Darwinian evolution
@nl
type
label
Waiting for two mutations: wit ...... limits of Darwinian evolution
@ast
Waiting for two mutations: wit ...... limits of Darwinian evolution
@en
Waiting for two mutations: wit ...... limits of Darwinian evolution
@nl
prefLabel
Waiting for two mutations: wit ...... limits of Darwinian evolution
@ast
Waiting for two mutations: wit ...... limits of Darwinian evolution
@en
Waiting for two mutations: wit ...... limits of Darwinian evolution
@nl
P2860
P1433
P1476
Waiting for two mutations: wit ...... limits of Darwinian evolution
@en
P2860
P304
P356
10.1534/GENETICS.107.082610
P407
P577
2008-11-01T00:00:00Z