Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans - Wikidata - wikimedia - TriplyDB

Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

http://www.wikidata.org/entity/Q24669542

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Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?Nitric oxide-modulating agents for gastrointestinal disorders Assessment and prevention of gastrointestinal toxicity of non-steroidal anti-inflammatory drugs Current approaches to prevent NSAID-induced gastropathy--COX selectivity and beyond Building a better aspirin: gaseous solutions to a century-old problem NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor.Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects.A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis Treatment strategies for osteoarthritis patients with pain and hypertension.Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential.Role of nitric oxide in the gastrointestinal tract Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells.Treatment of osteoarthritis in hypertensive patients.NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies Managing the adverse effects of nonsteroidal anti-inflammatory drugs.NSAIDs: take with food or after fasting?Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy.An overview of history, pathogenesis and treatment of perforated peptic ulcer disease with evaluation of prognostic scoring in adults.Recent developments in chimeric NSAIDs as safer anti-inflammatory agents.Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety.Endoscopic evaluation of the gastro-duodenal tolerance of short-term analgesic treatment with 25 mg diclofenac-K liquid capsules.Review article: a practical approach to the clinical management of NSAID enteropathy.Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582.Prevention and management of non-steroidal anti-inflammatory drugs-induced small intestinal injury.Direct gas measurements indicate that the novel cyclooxygenase inhibitor AZD3582 is an effective nitric oxide donor in vivo.Non-steroidal anti-inflammatory drug-induced enteropathy.Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice.Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD)

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P2860

Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

http://www.wikidata.org/entity/Q24669542

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2003 nî lūn-bûn

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P2860

Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen

Selective COX-2 Inhibitors, NSAIDs, aspirin, and myocardial infarction

Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat

Comparison of effects of calcium carbasalate and aspirin on gastroduodenal mucosal damage in human volunteers.

Role of nitric oxide in renal hemodynamics.

Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an underrecognized public health problem.

Nitric oxide in mucosal defense: a little goes a long way.

Nonsteroidal anti-inflammatory drug gastropathy.

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