Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex - Wikidata - wikimedia - TriplyDB

Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex

Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex

http://www.wikidata.org/entity/Q24670254

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Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermath Isothiocyanates Are Promising Compounds against Oxidative Stress, Neuroinflammation and Cell Death that May Benefit Neurodegeneration in Parkinson's Disease Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity Intermediate filaments take the heat as stress proteins.Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice.Randomized, split-body, single-blinded clinical trial of topical broccoli sprout extract: Assessing the feasibility of its use in keratin-based disorders.Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening.Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia.Keratinocyte-based cell assays: their potential pitfalls.Self-organization of keratin intermediate filaments into cross-linked networks PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding.A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair Nrf2 links epidermal barrier function with antioxidant defense The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress.Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions High-Throughput Screening for Drugs that Modulate Intermediate Filament Proteins Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes.Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero."IF-pathies": a broad spectrum of intermediate filament-associated diseases.Keratins and protein synthesis: the plot thickens Transcriptional responses of neonatal mouse lung to hyperoxia by Nrf2 status.Impact of epigenetic dietary compounds on transgenerational prevention of human diseases.Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility.Keratins and disease at a glance.Lessons from Animal Models of Cytoplasmic Intermediate Filament Proteins.Isothiocyanates inhibit psoriasis-related proinflammatory factors in human skin.Oxidative stress management in the hair follicle: Could targeting NRF2 counter age-related hair disorders and beyond?Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in vitro model for testing new treatments.Dermatology in the postgenomic era: harnessing human variation for personalized medicine.Types I and II Keratin Intermediate Filaments.

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Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex

http://www.wikidata.org/entity/Q24670254

description

2007 nî lūn-bûn

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2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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name

Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Proceedings of the National Academy of Sciences of the United States of America

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Reprogramming of keratin biosy ...... epidermolysis bullosa simplex

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Daryle DePianto

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Michelle L Kerns

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Paul Talalay

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Pierre A Coulombe

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P2860

A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.

MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

Gene targeting studies begin to reveal the function of neurofilament proteins

A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells

Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

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104

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Albena T Dinkova-Kostova

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