Common genetic polymorphisms affect the human requirement for the nutrient choline - Wikidata - wikimedia - TriplyDB

Common genetic polymorphisms affect the human requirement for the nutrient choline

Common genetic polymorphisms affect the human requirement for the nutrient choline

http://www.wikidata.org/entity/Q24672065

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Dietary choline requirements of women: effects of estrogen and genetic variation Choline: an essential nutrient for public health Epigenetic mechanisms for nutrition determinants of later health outcomes Sex and menopausal status influence human dietary requirements for the nutrient choline Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes Choline metabolism and risk of breast cancer in a population-based study Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted Sharpening Precision Medicine by a Thorough Interrogation of Metabolic Individuality Choline dehydrogenase polymorphism rs12676 is a functional variation and is associated with changes in human sperm cell function Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus Dietary docosahexaenoic acid supplementation modulates hippocampal development in the Pemt-/- mouse.Gene-gene interactions in the folate metabolic pathway and the risk of conotruncal heart defects Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival.Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups.The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates.Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma.Deletion of murine choline dehydrogenase results in diminished sperm motility.Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline.Choline's role in maintaining liver function: new evidence for epigenetic mechanisms.Polymorphisms and disease: hotspots of inactivation in methyltransferases What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders.Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants Nutritional genomics: defining the dietary requirement and effects of choline Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency.Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations.Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans.Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements.Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood.The supply of choline is important for fetal progenitor cells.Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas A grand challenge for nutrigenomics.Improved method for quantitative analysis of methylated phosphatidylethanolamine species and its application for analysis of diabetic-mouse liver samples.Choline intake in a large cohort of patients with nonalcoholic fatty liver disease.Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones.Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort

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P2860

Common genetic polymorphisms affect the human requirement for the nutrient choline

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2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Common genetic polymorphisms affect the human requirement for the nutrient choline

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Jiannan Song

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Joseph A Galanko

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Kerry-Ann da Costa

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Leslie M Fischer

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Olga G Kozyreva

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P2860

Finishing the euchromatic sequence of the human genome

Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD)

Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans.

Choline, an essential nutrient for humans

The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes

Sexually dimorphic activation of liver and brain phosphatidylethanolamine N-methyltransferase by dietary choline deficiency

Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene

Whole-genome shotgun assembly and comparison of human genome assemblies.

High-level multiplex genotyping of polymorphisms involved in folate or homocysteine metabolism by matrix-assisted laser desorption/ionization mass spectrometry.

Concentrations of choline-containing compounds and betaine in common foods.

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