Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
about
Reverse engineering of the spindle assembly checkpointStructural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionStable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3.Structural basis for recruitment of BRCA2 by PALB2A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingBuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignmentThe crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochoresBub3-BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomesDefining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 InhibitionStructural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1Structure and function of WD40 domain proteinsBub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingMad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochoreMad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpointIn-silico modeling of the mitotic spindle assembly checkpointSystematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshinThe dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregationIdentifying the hotspots on the top faces of WD40-repeat proteins from their primary sequences by β-bulges and DHSW tetradsBimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signalingHow chromosome mis-segregation leads to cancer: lessons from BubR1 mouse modelsMolecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancerKinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegansBub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression.A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1.BUB1 and BUBR1: multifaceted kinases of the cell cycle.Structure, function and mechanism of the anaphase promoting complex (APC/C).Structural insights into anaphase-promoting complex function and mechanism.Mitotic checkpoint control and chromatin remodeling.On the molecular mechanisms of mitotic kinase activation.Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms.Centromeres and kinetochores of Brassicaceae.Signalling dynamics in the spindle checkpoint response.Spatial rule-based modeling: a method and its application to the human mitotic kinetochore.Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells.ECRG2 disruption leads to centrosome amplification and spindle checkpoint defects contributing chromosome instability.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.
P2860
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P2860
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@ast
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@en
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@nl
type
label
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@ast
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@en
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@nl
prefLabel
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@ast
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@en
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@nl
P2093
P2860
P3181
P356
P1476
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
@en
P2093
Jawdat Al-Bassam
Nicholas A Larsen
Ronnie R Wei
Stephen C Harrison
P2860
P304
P3181
P356
10.1073/PNAS.0610358104
P407
P577
2007-01-23T00:00:00Z