Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells - Wikidata - wikimedia - TriplyDB

Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells

Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells

http://www.wikidata.org/entity/Q24672294

about

Drosophila SPF45: a bifunctional protein with roles in both splicing and DNA repair Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia U2AF-homology motif interactions are required for alternative splicing regulation by SPF45 U2AF homology motifs: protein recognition in the RRM world Splicing Regulation: A Molecular Device to Enhance Cancer Cell Adaptation Splicing Regulators and Their Roles in Cancer Biology and Therapy DNA copy number alterations and expression of relevant genes in triple-negative breast cancer Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1 Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.Mitogen-activated protein kinase phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splicing site utilization, proliferation, and cell adhesion.Evidence for large inversion polymorphisms in the human genome from HapMap data Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays.Regulation of chemoresistance via alternative messenger RNA splicing Evaluation of Caspase-9b and PP2Acα2 as potential biomarkers for chronic lymphocytic leukemia.Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis.Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors.Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.Deregulation of splicing factors and breast cancer development.Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.The PTB-Associated Splicing Factor/Peroxisome Proliferator-Activated Receptor Gamma Axis Regulates Autophagosome Formation in Human Pancreatic Cancer Cells.The emerging role of splicing factors in cancer.Molecular mechanisms regulating the tumor-targeting potential of splice-activated gene expression.Downregulation of RNA binding motif protein 17 expression inhibits proliferation of hypopharyngeal carcinoma FaDu cells.Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype.A computational framework for complex disease stratification from multiple large-scale datasets.

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P2860

Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells

http://www.wikidata.org/entity/Q24672294

description

2003 nî lūn-bûn

@nan

2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

@wuu

name

Human SPF45, a splicing factor ...... g-resistant phenotype to cells

@ast

Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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type

label

Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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prefLabel

Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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Human SPF45, a splicing factor ...... g-resistant phenotype to cells

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The American Journal of Pathology

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Human SPF45, a splicing factor ...... g-resistant phenotype to cells

@en

P2093

Anne H Dantzig

http://www.w3.org/2001/XMLSchema#string

George E Sandusky

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Janardhan Sampath

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Mark Rolfe

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Mark Williamson

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Pandy R Long

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Robert E Moore

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Robert L Shepard

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Viswanath Devanarayan

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William L Perry

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P2860

Primary structure of a human arginine-rich nuclear protein that colocalizes with spliceosome components

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

Large-scale proteomic analysis of the human spliceosome

Basic local alignment search tool

Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45

Modification of alternative splicing pathways as a potential approach to chemotherapy.

Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation.

The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics.

Mammalian ABC transporters in health and disease.

Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product.

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1781-90

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scholarly article

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1859461

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10.1016/S0002-9440(10)63538-9

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5

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163

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2003-11-01T00:00:00Z

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14578179

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multiple drug resistance

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1892446

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