The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint - Wikidata - wikimedia - TriplyDB

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

http://www.wikidata.org/entity/Q24675117

about

The pseudo GTPase CENP-M drives human kinetochore assembly Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B Mitotic regulation of the human anaphase-promoting complex by phosphorylation Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.Shugoshin collaborates with protein phosphatase 2A to protect cohesin Aurora B and 14-3-3 coordinately regulate clustering of centralspindlin during cytokinesis Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly An ECT2-centralspindlin complex regulates the localization and function of RhoA Genome stability is ensured by temporal control of kinetochore-microtubule dynamics Aurora B -TACC1 protein complex in cytokinesis Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody Recruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cells The chromosome cycle: coordinating replication and segregation. Second in the cycles review series.Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP Kinetochore-microtubule interactions: steps towards bi-orientation Towards a quantitative understanding of mitotic spindle assembly and mechanics Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.Linking kinetochore-microtubule binding to the spindle checkpoint Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres Death receptor-induced apoptosis reveals a novel interplay between the chromosomal passenger complex and CENP-C during interphase Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs The Dawn of Aurora Kinase Research: From Fly Genetics to the Clinic The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling DNA damage associated with mitosis and cytokinesis failure Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation Cell division: control of the chromosomal passenger complex in time and space The current view for the silencing of the spindle assembly checkpoint KNL1: bringing order to the kinetochore

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

http://www.wikidata.org/entity/Q24675117

description

2003 nî lūn-bûn

@nan

2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

The small molecule Hesperadin ...... he spindle assembly checkpoint

@ast

The small molecule Hesperadin ...... he spindle assembly checkpoint

@en

The small molecule Hesperadin ...... he spindle assembly checkpoint

@nl

type

label

The small molecule Hesperadin ...... he spindle assembly checkpoint

@ast

The small molecule Hesperadin ...... he spindle assembly checkpoint

@en

The small molecule Hesperadin ...... he spindle assembly checkpoint

@nl

prefLabel

The small molecule Hesperadin ...... he spindle assembly checkpoint

@ast

The small molecule Hesperadin ...... he spindle assembly checkpoint

@en

The small molecule Hesperadin ...... he spindle assembly checkpoint

@nl

P1433

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Journal of Cell Biology

P1476

The small molecule Hesperadin ...... he spindle assembly checkpoint

@en

P2093

Armin Heckel

http://www.w3.org/2001/XMLSchema#string

Christine Zimmer

http://www.w3.org/2001/XMLSchema#string

Conly L Rieder

http://www.w3.org/2001/XMLSchema#string

Gisela Schnapp

http://www.w3.org/2001/XMLSchema#string

Jacques van Meel

http://www.w3.org/2001/XMLSchema#string

Rainer Walter

http://www.w3.org/2001/XMLSchema#string

Richard W Cole

http://www.w3.org/2001/XMLSchema#string

Sabrina LaTerra

http://www.w3.org/2001/XMLSchema#string

Silke Hauf

http://www.w3.org/2001/XMLSchema#string

P2860

Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity

Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores

Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Distinct chromosome segregation roles for spindle checkpoint proteins.

The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

P304

281-94

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scholarly article

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585252

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10.1083/JCB.200208092

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P433

2

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P478

161

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Jan-Michael Peters

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2003-04-28T00:00:00Z

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10794709

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12707311

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2172906

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