Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms - Wikidata - wikimedia - TriplyDB

Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms

Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms

http://www.wikidata.org/entity/Q24676404

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Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets.The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling.CSPG4: a prototype oncoantigen for translational immunotherapy studies.Antibody therapies for melanoma: new and emerging opportunities to activate immunity (Review).Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4 Serum free cultured bone marrow mesenchymal stem cells as a platform to characterize the effects of specific molecules CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer FH535 inhibited migration and growth of breast cancer cells.FGF2 binding, signaling, and angiogenesis are modulated by heparanase in metastatic melanoma cells NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature.A gene expression signature associated with survival in metastatic melanoma Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B.Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration.CSPG4 as a target of antibody-based immunotherapy for malignant mesothelioma New approaches in metastatic melanoma: biological and molecular targeted therapies.NG2/CSPG4-collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion.Focal adhesion kinase: a promising target for anticancer therapy.NG2 expression in microglial cells affects the expression of neurotrophic and proinflammatory factors by regulating FAK phosphorylation.Erythroid cells generated in the absence of specific β1-integrin heterodimers accumulate reactive oxygen species at homeostasis and are unable to mount effective antioxidant defenses.Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.Targeting 11q23 positive acute leukemia cells with high molecular weight-melanoma associated antigen-specific monoclonal antibodies Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition A role for the NG2 proteoglycan in glioma progression.Divergent Synthesis of Chondroitin Sulfate Disaccharides and Identification of Sulfate Motifs that Inhibit Triple Negative Breast Cancer.Functions of chondroitin sulfate and heparan sulfate in the developing brain.CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma.Roles of NG2 glial cells in diseases of the central nervous system.Targeting of the tumor necrosis factor receptor superfamily for cancer immunotherapy.Transduction of extracellular cues into cell polarity: the role of the transmembrane proteoglycan NG2.Chondroitin sulfate proteoglycan 4 as a target for chimeric antigen receptor-based T-cell immunotherapy of solid tumors.Functional roles of CSPG4/NG2 in chondrosarcoma.A novel approach for targeted elimination of CSPG4-positive triple-negative breast cancer cells using a MAP tau-based fusion protein.Implementation of infrared and Raman modalities for glycosaminoglycan characterization in complex systems.The CSPG4-specific monoclonal antibody enhances and prolongs the effects of the BRAF inhibitor in melanoma cells.Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanoma outgrowth in vitro and in vivo.RGD-xyloside conjugates prime glycosaminoglycans.

P2860

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P2860

Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms

http://www.wikidata.org/entity/Q24676404

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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Journal of Cell Biology

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Melanoma chondroitin sulfate p ...... ivation by distinct mechanisms

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P2093

Cheryl L Neudauer

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Christopher Wilson

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Hong Xia

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James B McCarthy

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Jianbo Yang

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Joji Iida

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Matthew A Price

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Melanie A Simpson

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Soldano Ferrone

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P2860

Crystal structure of a heparin- and integrin-binding segment of human fibronectin.

Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas

Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

Integrin signaling

FAK integrates growth-factor and integrin signals to promote cell migration

Signaling through focal adhesion kinase

A novel repeat in the melanoma-associated chondroitin sulfate proteoglycan defines a new protein family

The focal adhesion kinase--a regulator of cell migration and invasion

Melanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen

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881-91

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10.1083/JCB.200403174

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6

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165

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8496967

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15210734

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2172406

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