Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
about
Rac and Rho GTPases in cancer cell motility controlChronic Granulomatous Disease; fundamental stages in our understanding of CGDP-Rex2, a new guanine-nucleotide exchange factor for RacInvolvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidasesRho GTPases in hematopoiesis and hemopathiesThe molecular pathology of primary immunodeficienciesBench-to-bedside review: acute respiratory distress syndrome - how neutrophils migrate into the lung.Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and traffickingGenetic disorders coupled to ROS deficiencyMolecular diagnosis of chronic granulomatous diseaseCongenital defects in neutrophil dynamicsActin cytoskeletal defects in immunodeficiencyLeukocyte migration from a fish eye's viewFlow Cytometry, a Versatile Tool for Diagnosis and Monitoring of Primary ImmunodeficienciesNeutrophils: Between host defence, immune modulation, and tissue injuryA 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activityNADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen speciesThe Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanineA regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox.Molecular basis for Rac2 regulation of phagocyte NADPH oxidase.Differential gene expression analysis by RNA-seq reveals the importance of actin cytoskeletal proteins in erythroleukemia cells.Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancerActivation of the A(3) adenosine receptor inhibits fMLP-induced Rac activation in mouse bone marrow neutrophils.Vav activation and function as a rac guanine nucleotide exchange factor in macrophage colony-stimulating factor-induced macrophage chemotaxis.Towards routine screening of rare genetic diseases: the example of chronic granulomatous diseasePoly(ethylene glycol)-containing hydrogels promote the release of primary granules from human blood-derived polymorphonuclear leukocytesCytotoxic necrotizing factor type 1 production by uropathogenic Escherichia coli modulates polymorphonuclear leukocyte function.Leukocytes navigate by compass: roles of PI3Kgamma and its lipid productsRab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms.P67-phox (NCF2) lacking exons 11 and 12 is functionally active and leads to an extremely late diagnosis of chronic granulomatous disease (CGD)Evaluation of the process for superoxide production by NADPH oxidase in human neutrophils: evidence for cytoplasmic origin of superoxide.The general case for redox control of wound repair.Distinct innate immune phagocyte responses to Aspergillus fumigatus conidia and hyphae in zebrafish larvae.Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies.Purinergic regulation of neutrophil chemotaxis.Modulation of DNA binding properties of CCAAT/enhancer binding protein epsilon by heterodimer formation and interactions with NFkappaB pathway.Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infectionChemotactic signaling pathways in neutrophils: from receptor to actin assembly.Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice.
P2860
Q21245504-C5293207-91B2-476E-AF65-78C96F1DD508Q21245653-5EEF7911-8329-4DB5-BB40-7EAA3EF6CC16Q24300899-624DFEC8-AAAE-4418-81F3-7A4C9033CB9FQ24548021-9737217D-D8D5-444C-B12D-E6292B5BD2B0Q24652636-6DDEE818-829F-462D-98EA-CE94EA77F94BQ24685932-F098330E-DDD5-4F46-9BBE-08D037E41861Q24800620-E0825C1D-99C6-4C46-99D4-50AC4A7BF9ABQ26781628-B976C802-9DAE-4428-9D6C-CA801C8313D3Q26799545-CDC3A0BB-CE1A-4ADD-BAFA-14747C66B5D6Q26865924-D3FB61DD-0F2F-4A03-845C-E90B0CF99D8CQ26996029-D02841B7-D5F1-4F21-8859-0E5805F66334Q27021852-F91D10C0-7C9E-423C-B508-BFDD4C3AE617Q27025000-6ED4A3BA-CA3F-48B5-95E0-1EB0632A3159Q28076919-61537385-4072-4354-A81A-46DD5814E276Q28087227-AC04B2E4-1185-48A5-B7A4-484E26E25F30Q28214913-09566923-C68F-41C7-B705-CB3F02305DA6Q28247419-3B5EB7F4-81B8-468E-8821-1116BDAA4603Q28282131-BA9A036F-D61B-456B-A50A-AC1209939875Q28646167-C22ED074-E7E7-4B95-AB90-2F81E21BBCBEQ30478913-E988B2DE-16DE-40F2-8B92-47FCC523D930Q32063730-41950746-08E5-4FB2-AB48-50B7157BBCE7Q32186337-255FBEE5-C1C3-4F70-88F1-539A267747BDQ33591690-98B69032-A11E-4E53-9B91-6D6547BD9854Q33759296-36A7A58B-C4DF-425E-A11D-F71396486AC6Q33770461-4B65F3EB-5351-40A6-B54E-2E69E15926E2Q33813818-CB1B4C9D-423D-41E4-A6A1-6E487FB6CEBEQ34000502-96BE3E23-9CCB-4222-B423-AD0FFA07C15EQ34034054-D2275151-B675-4C61-9600-45D5D90C2FBFQ34069723-248DC61F-3916-4B1B-B91E-8B79235ACCD1Q34118192-5F823F18-C6A8-47CC-A031-720CDEBD3B3AQ34238532-C50B0266-F28C-4786-A9A5-E861306DA802Q34238897-07413F26-78D0-4D20-B2C7-A35733C9416FQ34276805-C47BCD64-ABDD-4E09-BEB9-65B85B5A552AQ34297696-EAD4C1AD-BE1C-4B90-9ADC-3782215937B2Q34375180-8A6B3FDC-71B8-42A6-A3D4-C1183B988394Q34425713-EA672166-F922-4899-B9A6-415A8B7E907DQ34606551-965FC5DF-141F-433C-A51F-03419764314CQ34684714-46C6690D-80E5-43EF-A362-7825FA1FF103Q34713881-447950AB-2A75-4938-8A24-385C4B04724FQ34724992-52BBF28A-DE7E-4295-8C7A-7D617AB37AF2
P2860
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@ast
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@en
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@nl
type
label
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@ast
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@en
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@nl
prefLabel
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@ast
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@en
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@nl
P2093
P2860
P356
P1476
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
@en
P2093
A Kurkchubasche
C Gonzalez-Aller
D R Ambruso
G L Johnson
J Panepinto
P2860
P304
P356
10.1073/PNAS.080074897
P407
P577
2000-04-25T00:00:00Z