Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage
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Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with NumbThe gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signalingAbl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinasesSiah-1 binds and regulates the function of NumbMouse numb is an essential gene involved in cortical neurogenesisMolecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cellsAdapting for endocytosis: roles for endocytic sorting adaptors in directing neural development.Harnessing the power of the endosome to regulate neural development.Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer.Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes.Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors.Notch is a critical regulator in cervical cancer by regulating Numb splicing.Alternative splicing is frequent during early embryonic development in mouse.Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel.Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway.Role of stem cells in cardiovascular biology.Cellular studies of auditory hair cell regeneration in birdsThe tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma.Two novel human NUMB isoforms provide a potential link between development and cancer.Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain-containing m-Numb protein expression in regenerating gastric mucosa.The clathrin adaptor proteins ARH, Dab2, and numb play distinct roles in Niemann-Pick C1-Like 1 versus low density lipoprotein receptor-mediated cholesterol uptake.Numb protects renal proximal tubular cells from puromycin aminonucleoside-induced apoptosis through inhibiting Notch signaling pathway.NumbL is essential for Xenopus primary neurogenesis.The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.Role of Numb expression and nuclear translocation in endometrial cancer.Pre-mRNA splicing modulations in senescence.Alternative splicing of VEGFA, APP and NUMB genes in colorectal cancerAre genetic determinants of asymmetric stem cell division active in hematopoietic stem cells?Genetic variants of numb gene were associated with elevated total cholesterol level and low density lipoprotein cholesterol level in Chinese subjects, in Xinjiang, China.The association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China.Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma.Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during developmentPro- and anti-mitogenic actions of pituitary adenylate cyclase-activating polypeptide in developing cerebral cortex: potential mediation by developmental switch of PAC1 receptor mRNA isoformsNumb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesisNumb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.RBFOX1 and RBFOX2 are dispensable in iPSCs and iPSC-derived neurons and do not contribute to neural-specific paternal UBE3A silencing.RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expressionNotch signaling in embryonic and adult myelopoiesis.
P2860
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P2860
Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@ast
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@en
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@nl
type
label
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@ast
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@en
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@nl
prefLabel
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@ast
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@en
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@nl
P2093
P2860
P3181
P356
P1476
Distinct human NUMB isoforms r ...... ration in the neuronal lineage
@en
P2093
A Bashirullah
D E Goldhawk
H D Lipshitz
S O Meakin
P2860
P304
P3181
P356
10.1073/PNAS.96.18.10472
P407
P577
1999-08-31T00:00:00Z