Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation
about
Evidence for a high-spin Fe(IV) species in the catalytic cycle of a bacterial phenylalanine hydroxylaseMeasurement of intrinsic rate constants in the tyrosine hydroxylase reactionMechanisms of tryptophan and tyrosine hydroxylase.Versatility of biological non-heme Fe(II) centers in oxygen activation reactions.Pulsed EPR study of amino acid and tetrahydropterin binding in a tyrosine hydroxylase nitric oxide complex: evidence for substrate rearrangements in the formation of the oxygen-reactive complex.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Kinetic mechanism of phenylalanine hydroxylase: intrinsic binding and rate constants from single-turnover experiments.Single turnover kinetics of tryptophan hydroxylase: evidence for a new intermediate in the reaction of the aromatic amino acid hydroxylases.Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylaseDemonstration of a peroxide shunt in the tetrahydropterin-dependent aromatic amino acid monooxygenases.Characterization of metal ligand mutants of phenylalanine hydroxylase: Insights into the plasticity of a 2-histidine-1-carboxylate triad.Identification of phenylalanine 3-hydroxylase for meta-tyrosine biosynthesis.Kinetic isotope effects on aromatic and benzylic hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase as probes of chemical mechanism and reactivity.Allelopathic effects of exogenous phenylalanine: a comparison of four monocot species.Nucleophilic reactivity of a copper(II)-superoxide complex.
P2860
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P2860
Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Insights into the catalytic me ...... ects on aromatic hydroxylation
@ast
Insights into the catalytic me ...... ects on aromatic hydroxylation
@en
Insights into the catalytic me ...... ects on aromatic hydroxylation
@nl
type
label
Insights into the catalytic me ...... ects on aromatic hydroxylation
@ast
Insights into the catalytic me ...... ects on aromatic hydroxylation
@en
Insights into the catalytic me ...... ects on aromatic hydroxylation
@nl
prefLabel
Insights into the catalytic me ...... ects on aromatic hydroxylation
@ast
Insights into the catalytic me ...... ects on aromatic hydroxylation
@en
Insights into the catalytic me ...... ects on aromatic hydroxylation
@nl
P2860
P356
P1433
P1476
Insights into the catalytic me ...... ects on aromatic hydroxylation
@en
P2093
Jorge Alex Pavon
Paul F Fitzpatrick
P2860
P304
P356
10.1021/BI0607554
P407
P577
2006-09-12T00:00:00Z