KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. - Wikidata - wikimedia - TriplyDB

KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.

KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.

http://www.wikidata.org/entity/Q24681227

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Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects Sestrins at the crossroad between stress and aging Drosophila tools and assays for the study of human diseases Methods to assess Drosophila heart development, function and aging Comparative approaches to the study of physiology: Drosophila as a physiological tool.Genetic variation for cardiac dysfunction in Drosophila Arrhythmia caused by a Drosophila tropomyosin mutation is revealed using a novel optical coherence tomography instrument Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart A Drosophila model of high sugar diet-induced cardiomyopathy The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model Optogenetic pacing in Drosophila melanogaster SPARC-Dependent Cardiomyopathy in Drosophila.Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart Exercise-training in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performance Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner Automatic filtering and substantiation of drug safety signals Inhibition of ion channels and heart beat in Drosophila by selective COX-2 inhibitor SC-791 Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species Non-invasive Drosophila ECG recording by using eutectic gallium-indium alloy electrode: a feasible tool for future research on the molecular mechanisms involved in cardiac arrhythmia Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies Obesity-associated cardiac dysfunction in starvation-selected Drosophila melanogaster KCNQ channels show conserved ethanol block and function in ethanol behaviour.Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype.A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila ROS regulate cardiac function via a distinct paracrine mechanism.Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis.A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function.Serial examination of an inducible and reversible dilated cardiomyopathy in individual adult Drosophila.Novel trigenic CACNA1C/DES/MYPN mutations in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome.

P2860

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P2860

KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.

http://www.wikidata.org/entity/Q24681227

description

2007 nî lūn-bûn

@nan

2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

KCNQ potassium channel mutatio ...... hat mimic the effects of aging

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KCNQ potassium channel mutatio ...... hat mimic the effects of aging

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KCNQ potassium channel mutatio ...... at mimic the effects of aging.

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KCNQ potassium channel mutatio ...... hat mimic the effects of aging

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Proceedings of the National Academy of Sciences of the United States of America

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KCNQ potassium channel mutatio ...... at mimic the effects of aging.

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P2093

H-S Vincent Chen

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James W Posakony

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Joseph M Metzger

http://www.w3.org/2001/XMLSchema#string

Karen Ocorr

http://www.w3.org/2001/XMLSchema#string

Martin Fink

http://www.w3.org/2001/XMLSchema#string

Nick L Reeves

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Robert J Wessells

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Rolf Bodmer

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Soichiro Yasuda

http://www.w3.org/2001/XMLSchema#string

Takeshi Akasaka

http://www.w3.org/2001/XMLSchema#string

P2860

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

Kir6.2 is required for adaptation to stress.

Pacing stress echocardiography.

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Physiological and pathophysiological roles of ATP-sensitive K+ channels

NK-2 homeobox genes and heart development

Atrial fibrillation as an independent risk factor for stroke: the Framingham Study

Drosophila as a model for the identification of genes causing adult human heart disease.

Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.

Neuronal KCNQ potassium channels: physiology and role in disease.

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6447674

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17360457

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heart arrhythmia

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1820688

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