Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.
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Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeletonThe integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreadingStructural basis for paxillin binding and focal adhesion targeting of β-parvinTargeting and activation of Rac1 are mediated by the exchange factor beta-Pix.Pak1 and PIX regulate contact inhibition during epithelial wound healingBrk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasionGIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnoverA novel GTPase-activating protein for ARF6 directly interacts with clathrin and regulates clathrin-dependent endocytosis.Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayActivation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complexThe association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assemblyA PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migrationHic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinaseCoupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassemblyFocal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophyA truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylationAn ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organizationPaxillin comes of ageMultiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivityPAG3/Papalpha/KIAA0400, a GTPase-activating protein for ADP-ribosylation factor (ARF), regulates ARF6 in Fcgamma receptor-mediated phagocytosis of macrophagesThe integrin-actin connection, an eternal love affairPhosphorylation of actopaxin regulates cell spreading and migrationACAPs are arf6 GTPase-activating proteins that function in the cell peripheryActopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesionThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationLIM domains target actin regulators paxillin and zyxin to sites of stress fiber strainPhosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnoverThe non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1GIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 MotifsStructural Analysis of the Interactions Between Paxillin LD Motifs and α-ParvinMolecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3)Role for Gcs1p in regulation of Arl1p at trans-Golgi compartmentsAltered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteinsGIT proteins, A novel family of phosphatidylinositol 3,4, 5-trisphosphate-stimulated GTPase-activating proteins for ARF6Association of the kinesin motor KIF1A with the multimodular protein liprin-alphaActin cytoskeletal association of cytohesin-1 is regulated by specific phosphorylation of its carboxyl-terminal polybasic domainAGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton
P2860
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P2860
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Paxillin LD4 motif binds PAK a ...... ole in cytoskeletal remodeling
@nl
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@ast
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@en
type
label
Paxillin LD4 motif binds PAK a ...... ole in cytoskeletal remodeling
@nl
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@ast
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@en
prefLabel
Paxillin LD4 motif binds PAK a ...... ole in cytoskeletal remodeling
@nl
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@ast
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@en
P2093
P2860
P3181
P356
P1476
Paxillin LD4 motif binds PAK a ...... le in cytoskeletal remodeling.
@en
P2093
A R McDonald
C E Turner
J A Perrotta
P S Leventhal
S Bagrodia
S N Nikolopoulos
P2860
P304
P3181
P356
10.1083/JCB.145.4.851
P407
P577
1999-05-01T00:00:00Z